Avanti® Polar Lipids: Lipidomics - Approaches for Profiling, Analysis and Cellular Signaling Studies

Avanti Polar Lipids

 Pure Lipids for Many Applications

Whether you are a seasoned lipid researcher or new to the field of lipid research, the Avanti® lipidomics division is developing revolutionary tools to provide you with better approaches to answer fundamental questions about lipid structure and function.

 Standards for Quantitative Mass Spectrometry

Precision in Lipid Mass Spec

You need well-defined internal standards to identify the structure or determine the accurate concentration of each molecular species in mass spec-based research. Whatever your application, Avanti® chemically pure synthetic lipid standards allow for precise quantization or identification of major lipid classes, including glycerolipids, glycerophospholipids, sphingolipids, and sterols.

  • Quantitative Standards are characterized and prepackaged in unit containers at defined concentrations. A detailed Certificate of Analysis accompanies the standard, and the stability is monitored by QC staff.
  • Qualitative Standards for general identification of lipids by mass spec analysis.

Monoclonal Antibodies

Lipid Binding Antibodies for Signaling and Disease Research

Studying the role of lipids as cofactors, agonists, or antagonists in cellular signaling events is increasingly common. Use Avanti® monoclonal antibodies against bioactive lipids to detect the presence of these species or the downstream signals that they stimulate. Add another dimension to your basic signaling and disease research.

  • E06 discriminates between native LDL and OxLDL by binding to the phosphocholine headgroup of oxidized phospholipid that is present in OxLDL but is absent from native LDL.
  • WR304 can be used to probe the presence of PIP and PIP2.

 Lipid Toolbox

Get a Better Understanding of Lipid Functions

A lipid toolbox of integrated methodologies is essential in understanding the functional role of lipids in biological systems. Avanti® tools help you probe protein-lipid interactions, develop enhanced systems for the cellular delivery of lipids, and perform robust assays.

  • Lipid Snoopers®. Nitrocellulose membranes or 8-well ELISA strips that are ideal for investigating protein-lipid interactions.
  • Huzzah® improves the cellular delivery of lipid species through their conjugation with human serum albumin (HSA).
  • CerS Assay Kit. Easy-to-use assay for measuring ceramide synthase (CerS) activity in biological samples.

Polar Bear photo provided by: Kyriakos Kaziras