Avanti® Polar Lipids: Pure Expertise in Lipids Research Products

You don’t have to be a lipid specialist when you order from someone who is. We’ve partnered with Avanti® Polar Lipids to make high-purity lipids more accessible to researchers around the world. Lipids can be unpredictable and unstable. Choose Avanti® products and stop inferior lipids from jeopardizing your experiments. The Avanti® team has consistently led the industry to create pure lipids, winning many awards along the way. All Avanti® products available on SigmaAldrich.com meet stringent quality and stability control standards.

 Avanti® Polar Lipids

 UltimateSPLASH® ONE Internal Standard

One vial containing 69 high-purity deuterium labeled internal standards covering 15 lipid classes. Each vial contains 1.2mL of 1:1 DCM:MeOH solution that has been meticulously characterized, quantitated, and blended for accurate quantitation using multiple lipidomics techniques.

 Immunotherapy & Vaccine Development

Monophosphoryl Lipid A (MPL) Adjuvants

Vaccine adjuvants using heterogeneous monophosphoryl Lipid A (MPL) derived from Salmonella minnesota R595 have proven to be safe and effective at inducing Th-1 type immune responses to heterologous proteins in animal and human vaccines. The Avanti® team revolutionized immunotherapy and vaccine development with the introduction of synthetic MPL derivatives and adjuvant systems. We also offer multiple Avanti® synthetic analogs of MPL containing a single molecular species that have been shown to be effective and safe at inducing an immune response as their natural product predecessor.

PHAD®, 3D-PHAD®, and 3D(6A)-PHAD® have been tested extensively in animals using a variety of antigens. In all cases, these adjuvants exhibit a similar activity and safety profile to bacterially-derived MPL.