Tachykinnin - Receptor Agonists

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G113 GR 64349 >96% GR 64349 peptide acts as an agonist of neurokinin (NK2) receptor, which leads to reduced NK2 response to kainate and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), but not to NMDA (N-methyl-D-aspartate).
human ... TACR2(6865)
mouse ... TACR2(21337)
rat ... TACR2(25007)
G114 GR 73632 >97% GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.
human ... TAC1(6863), TACR1(6869)
mouse ... TAC1(21333), TACR1(21336)
rat ... TAC1(24806), TACR1(24807)
H1664 Hemokinin 1 human ≥98% (HPLC), solid Hemokinin 1 (HK1) is an endogenous agonist for all tachykinin receptors. However, it is highly selective for the NK1 (neurokinin 1) receptor. HK1 and substance-P compete with each other for binding to NK1. HK1 is involved in the B-cell as well as T-cell development.
NK1 tachykinin receptor agonist.
human ... TAC4(255061)
N4267 Neurokinin A ≥97% (HPLC) Endogenous tachykinin agonist with preference for the NK-2 receptor, more potent bronchoconstrictor than Substance P.
human ... TAC1(6863)
N4143 Neurokinin B ≥95% (HPLC) Endogenous tachykinin agonist with preference for the NK-3 receptor. Potent bronchoconstrictor; may have neuromodulatory role in brain.
human ... TAC3(6866)
S6883 Substance P acetate salt hydrate ≥95% (HPLC), powder NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents.
human ... TAC1(6863)
S3672 [Sar9, Met(O2)11]-Substance P ≥95% (HPLC) Highly selective NK-1 receptor agonist.
human ... TACR1(6869)
mouse ... TACR1(21336)
rat ... TACR1(24807)
S2275 Acetyl-[Arg6, Sar9, Met(O2)11]-Substance P Fragment 6-11 ≥95% Selective NK-1 receptor agonist.
human ... TAC1(6863)