Lipodisq® Reagents

Lipodisq reagents are novel polymers derived from styrene and maleic acid. Lipodisq polymers are capable of forming nanosized lipid-based discoidal particles capable of incorporating membrane proteins. The Lipodisq technology can solubilize commonly used lipids such as dimyristoylphosphatidylcholine (DMPC) without the use of detergents. Lipodisqs typically have a diameter of 9-10 nm at pH 7.4.

The Lipodisq reagents come in several defined ratios of styrene to maleic acid/anhydride. The functional pH ranges of the different Lipodisq reagent grades are as follows:
  • SMA 1:1: pH range of 3.5 - 5.5
  • SMA 2:1: pH range of 5.5 - 8.0
  • SMA 3:1: pH range of 6.0 - 9.0
  • SMA 4:1: pH range of 8.5 - 10.5

Lipodisq is a registered trademark of Malvern Cosmeceutics Limited

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L9170 Lipodisq® Styrene:Maleic Anhydride Copolymer 3:1, Pre-hydrolyzed
L8920 Lipodisq® Styrene:Maleic Anhydride Copolymer 2:1
L9045 Lipodisq® Styrene:Maleic Anhydride Copolymer 3:1
SAE0062 Lipodisq® Styrene:Maleic Anhydride Copolymer 2:1, Pre-hydrolyzed
SAE0079 Lipodisq® Styrene:Maleic Anhydride Copolymer 1:1 New
SAE0081 Lipodisq® Styrene:Maleic Anhydride Copolymer 4:1 New
SAE0080 Lipodisq® Styrene:Maleic Anhydride Copolymer 1:1, Pre-hydrolyzed New
SAE0082 Lipodisq® Styrene:Maleic Anhydride Copolymer 4:1, Pre-hydrolyzed New