Chromatographically Purified Collagenase

Chromatographically purified collagenase products have high specific activity against native triple-helical fibers of collagen and in the FALGPA synthetic peptide assay. Activity against undenatured collagen protein is given as CDU (collagen digestive units). The spectrophotometric FALGPA (N-[3-(-Furyll)acryloyl)]-Leu-Gly-Pro-Ala) assay gives quicker results than CDU for standardization purposes. We offer substrates for both assays. Type III preparations contain a small amount of proteolytic activity against casein, while type VII forms are free of both caseinase and clostripain activity. Several of the products are sterilized for use in cell culture.

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C0255 Collagenase from Clostridium histolyticum purified by chromatography, ≥1 FALGPA units/mg solid, ≥250 CDU/mg solid (CDU = collagen digestion units), lyophilized powder
C0773 Collagenase from Clostridium histolyticum high purity, purified by chromatography, Type VII, ≥4 FALGPA units/mg solid, lyophilized powder, 1,000-3,000 CDU/mg solid (CDU = collagen digestion units)
C2399 Collagenase from Clostridium histolyticum sterile-filtered, high purity, purified by chromatography, Type VII-S, ≥4 FALGPA units/mg solid, 1,000-3,000 CDU/mg solid
C2799 Collagenase from Clostridium histolyticum powder, suitable for cell culture, 1000-3000 CDU/mg solid (CDU = collagen digestion units), ≥4 FALGPA units/mg solid, high purity