MAP Kinase

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176900 Anthrax Lethal Factor, Recombinant, Bacillus anthracis, B. anthracis - Calbiochem  
178278 Apigenin - CAS 520-36-5 - Calbiochem Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 µM). C₁₅H₁₀O₅
19-134   p38/SAPK2 Inhibitor (SB 202190) The p38/SAPK2 Inhibitor (SB 202190) controls the biological activity of p38/SAPK2. This small molecule/inhibitor is primarily used for Biochemicals applications.  
19-135   p38/SAPK2 Inhibitor (SB 203580) The p38/SAPK2 Inhibitor (SB 203580) controls the biological activity of p38/SAPK2. This small molecule/inhibitor is primarily used for Biochemicals applications.  
19-143   PD 98059  
19-147   U0126 U0126 is a elective inhibitor of MEK-1 and MEK-2; weak inhibitor of PKC, Raf, ERK, JNK, MEKK, MKK-3, MKK-4/SEK, MKK-6, Abl, Cdk2 and Cdk4.  
317496 Dual Specificity Protein Phosphatase 1/6 Inhibitor, BCI - CAS 15982-84-0 - Calbiochem The Dual Specificity Protein Phosphatase 1/6 Inhibitor, BCI controls the biological activity of Dual Specificity Protein Phosphatase 1/6. Primarily used for Phosphorylation & Dephosphorylation apps. C₂₂H₂₃NO
328000 ERK Activation Inhibitor Peptide I, Cell-Permeable - Calbiochem The ERK Activation Inhibitor Peptide I, Cell-Permeable controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₈₆H₁₅₃N₁₉O₁₇S
328005 ERK Activation Inhibitor Peptide II, Cell-Permeable - Calbiochem The ERK Activation Inhibitor Peptide II, Cell-Permeable controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₃₆H₂₄₁N₅₃O₃₁S
328006-M ERK Inhibitor - CAS 1049738-54-6 - Calbiochem The ERK Inhibitor, also referenced under CAS 1049738-54-6, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₄H₁₆N₂O₃S • HCl
328007 ERK Inhibitor II, FR180204 - CAS 865362-74-9 - Calbiochem ERK Inhibitor II, FR 180204, CAS 865362-74-9, is a cell-permeable, potent, ATP-competitive inhibitor of ERK1 and ERK2 (IC₅₀ = 510 nM and 330 nM; Ki = 310 nM and 140 nM, respectively). C₁₈H₁₃N₇
328008 ERK Inhibitor II, Negative Control, FR180209 - CAS 1177970-73-8 - Calbiochem The ERK Inhibitor II, Negative Control, also referenced under CAS 1177970-73-8, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₈H₁₂N₆O
328009 ERK Inhibitor III - CAS 331656-92-9 - Calbiochem The ERK Inhibitor III, also referenced under CAS 331656-92-9, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₂H₁₀N₆O₅
328010 InSolution™ ERK Inhibitor II, FR180204 - Calbiochem The InSolution™ ERK Inhibitor II, FR180204, also referenced under CAS 865362-74-9, controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₈H₁₃N₇
385880 Hsp25 Kinase Inhibitor - Calbiochem The Hsp25 Kinase Inhibitor controls the biological activity of Hsp25 KInase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₆₁H₁₁₃N₂₁O₁₆
444180 MAP Kinase Inhibitor Set I - Calbiochem The MAP Kinase Inhibitor Set I controls the biological activity of MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.  
444189 InhibitorSelect™ MAP Kinase Signaling Pathway Inhibitor Panel The InhibitorSelect™ MAP Kinase Signaling Pathway Inhibitor Panel controls the biological activity of InhibitorSelect™.  
444190 MAP Kinase Inhibitor Set II - Calbiochem The MAP Kinase Inhibitor Set II controls the biological activity of MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.  
444968 InSolution™ MEK1/2 Inhibitor III, PD0325901 - CAS 391210-10-9 - Calbiochem InSolution™ MEK1/2 Inhibitor III, PD0325901, CAS 391210-10-9, is a 50 mM solution of MEK1/2 Inhibitor III, PD0325901 in DMSO. A cell-permeable, potent, non-competitive MEK/MAPKK/MKK inhibitor., The InSolution™ MEK1/2 Inhibitor III, PD0325901, also referenced under CAS 391210-10-9, controls the biological activity of MEK1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₆H₁₄F₃IN₂O₄
454861 MNK1 Inhibitor - CAS 522629-08-9 - Calbiochem The MNK1 Inhibitor, also referenced under CAS 522629-08-9, controls the biological activity of MNK1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₁H₉FN₆
454862 MNK1/2 Inhibitor II, ETP-45835 - Calbiochem The MNK1/2 Inhibitor II, ETP-45835 controls the biological activity of MNK1/2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₃H₁₆N₄•2HCl
475863 MK2a Inhibitor - CAS 41179-33-3 - Calbiochem The MK2a Inhibitor, also referenced under CAS 41179-33-3, controls the biological activity of MK2a. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₂H₂₀FNO₂
475864 MK-2 Inhibitor III - CAS 1186648-22-5 - Calbiochem MK-2 Inhibitor III, CAS 1186648-22-5, is a cell-permeable, ATP-competitive inhibitor of MK-2/MAPKAP-K2 (IC50 = 8.5, 81 & 210 nM against MK-2, MK-5 & MK-3, respectively)., The MK-2 Inhibitor III, also referenced under CAS 1186648-22-5, controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₁H₁₆N₄O • H₂O
475964 MK-2 Inhibitor IV, MK-25 - Calbiochem The MK-2 Inhibitor IV, MK-25 controls the biological activity of MK-2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₇H₂₅ClN₄O₂, HCl
480150-M Ras-Net (Elk-3) Pathway Inhibitor, XRP44X - CAS 729605-21-4 - Calbiochem The Ras-Net (Elk-3) Pathway Inhibitor, XRP44X, also referenced under CAS 729605-21-4, controls the biological activity of Ras-Net (Elk-3). C₂₁H₂₁ClN₄O
506121 p38 MAP Kinase Inhibitor III - CAS 581098-48-8 - Calbiochem The p38 MAP Kinase Inhibitor III, also referenced under CAS 581098-48-8, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₃H₂₁FN₄S
506126 p38 MAP Kinase Inhibitor - CAS 219138-24-6 - Calbiochem The p38 MAP Kinase Inhibitor, also referenced under CAS 219138-24-6, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₀H₁₃ClFN₃O
506148 InSolution™ p38 MAP Kinase Inhibitor III - Calbiochem InSolution p38 MAP Kinase Inhibitor III, CAS 581098-48-8, is a 10 mM solution in DMSO. A cell-permeable, potent, selective, ATP-competitive p38 MAP kinase inhibitor (IC50 = 380 nM for p38α)., The InSolution™ p38 MAP Kinase Inhibitor III controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₃H₂₁FN₄S
506153 p38 MAP Kinase Inhibitor IV - CAS 1638-41-1 - Calbiochem The p38 MAP Kinase Inhibitor IV, also referenced under CAS 1638-41-1, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₂H₄Cl₆O₄S
506156 p38 MAP Kinase Inhibitor V - CAS 271576-77-3 - Calbiochem The p38 MAP Kinase Inhibitor V, also referenced under CAS 271576-77-3, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₁₉H₂₀ClN₅
506157 p38 MAP Kinase Inhibitor VI, JX401 - CAS 349087-34-9 - Calbiochem The p38 MAP Kinase Inhibitor VI, JX401, also referenced under CAS 349087-34-9, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₁H₂₅NO₂S
506158 p38 MAP Kinase Inhibitor VII, SD-169 - CAS 1670-87-7 - Calbiochem The p38 MAP Kinase Inhibitor VII, SD-169, also referenced under CAS 1670-87-7, controls the biological activity of p38 MAP Kinase. C₉H₈N₂O
506163 p38 MAP Kinase Inhibitor VIII - CAS 321351-00-2 - Calbiochem The p38 MAP Kinase Inhibitor VIII, also referenced under CAS 321351-00-2, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₀H₁₆BrClN₂O
506172 p38 MAP Kinase Inhibitor X, BIRB 796 - CAS 285983-48-4 - Calbiochem p38 MAP Kinase Inhibitor X, BIRB 796, CAS 285983-48-4, is a cell-permeable, highly potent, slow binding, high affinity inhibitor of p38a (IC50 = 8 and 97 nM with or without 2 h preincubation)., The p38 MAP Kinase Inhibitor X, BIRB 796, also referenced under CAS 285983-48-4, controls the biological activity of p38 MAP Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₃₁H₃₇N₅O₃
513000 PD 98059 - CAS 167869-21-8 - Calbiochem PD 98059, CAS 167869-21-8, is a cell-permeable, selective & reversible inhibitor of MAP Kinase Kinase (MEK). Inhibits MAP Kinase activation and subsequent phosphorylation of MAP Kinase substrates. C₁₆H₁₃NO₃
513030 PD 169316 - CAS 152121-53-4 - Calbiochem A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC₅₀ = 89 nM). C₂₀H₁₃FN₄O₂
539644 UCN-01 A cell-permeable Staurosporine derived anticancer agent that reversibly and ATP-competitively inhibits several protein kinases. C₂₈H₂₆N₄O₄
559387 SB 202474 - CAS 172747-50-1 - Calbiochem C₁₇H₁₇N₃O
559388 SB 202190 - CAS 152121-30-7 - Calbiochem SB 202190, CAS 152121-30-7, is a potent, reversible, competitive inhibitor of p38. Inhibits p38 phosphorylation of myelin basic protein. Blocks the activity of p38β (Ki = 16 nM; IC₅₀ = 350 nM). C₂₀H₁₄FN₃O
559389 SB 203580 - CAS 152121-47-6 - Calbiochem SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC₅₀ = 34 nM in vitro, 600 nM in cells)., SB 203580, CAS 152121-47-6, is a highly specific, potent, cell-permeable, selective, reversible, and ATP-competitive inhibitor of p38 MAP kinase (IC₅₀ = 34 nM in vitro, 600 nM in cells). C₂₁H₁₆N₃OSF
559393-M SB 202190, Hydrochloride - CAS 350228-36-3 - Calbiochem A water-soluble form of the potent p38 MAP kinase inhibitor SB 202190. C₂₀H₁₄FN₃O · HCl
559395 SB 203580, Hydrochloride - CAS 869185-85-3 - Calbiochem SB 203580, Hydrochloride, CAS 869185-85-3, is a water-soluble form of SB 203580. A highly potent, selective, ATP-competitive inhibitor of p38 MAP Kinase (IC₅₀ = 34 nM in vitro, 600 nM in cells). C₂₁H₁₆FN₃OS · HCl
559396 SB 220025 A cell-permeable, potent, reversible, ATP-competitive, and specific inhibitor of human p38 MAP Kinase (IC₅₀ = 60 nM). C₁₈H₁₉FN₆
559397 InSolution™ SB 202190 - CAS 152121-30-7 - Calbiochem C₂₀H₁₄FN₃O
559398 InSolution™ SB 203580 - Calbiochem InSolution SB 203580, CAS 152121-47-6, is a 1 mg/ml solution of SB 203580 in DMSO. A cell-permeable, selective, reversible inhibitor of p38 MAP kinase (IC₅₀ = 34 nM in vitro, 600 nM in cells). C₂₁H₁₆FN₃OS
559399 SB 203580, Sulfone - CAS 152121-46-5 - Calbiochem C₂₁H₁₆FN₃O₂S
559400 SB 203580, Iodo- - CAS 189319-35-5 - Calbiochem A highly specific, cell-permeable, reversible, ATP-competitive, and potent inhibitor of p38 MAP kinase. C₂₁H₁₆IN₃OS
559404 SB 239063 - CAS 798558-40-4 - Calbiochem SB 239063, CAS 193551-21-2, is a cell-permeable, potent, reversible & ATP-competitive inhibitor of a- and b-isoforms (IC50 = 44 nM), but not g- or d-isoforms (IC50 greater than 100 µM) of MAP kinase p38., A potent, cell-permeable, reversible, and ATP-competitive inhibitor of the α- and β-isoforms (IC₅₀ = 44 nM), but not the γ- or δ-isoform (IC₅₀ > 100 µM), of MAP kinase p38. C₂₀H₂₁FN₄O₂
565625 SC-68376 - CAS 318480-82-9 - Calbiochem C₁₅H₁₂N₂O
567305 SKF-86002 - CAS 72873-74-6 - Calbiochem A cell-permeable, reversible, and ATP-competitive cytokine-suppressive anti-inflammatory drug (CSAID). C₁₆H₁₂FN₃S
616373 Tpl2 Kinase Inhibitor - CAS 871307-18-5 - Calbiochem Tpl2 Kinase Inhibitor, CAS 871307-18-5, is a cell-permeable, potent, reversible, and ATP-competitive inhibitor of Tpl2 kinase (IC50 = 50 nM)., The Tpl2 Kinase Inhibitor, also referenced under CAS 871307-18-5, controls the biological activity of Tpl2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. C₂₁H₁₄ClFN₆
616404 Tpl2 Kinase Inhibitor II - CAS 1186649-59-1 - Calbiochem C₂₂H₂₄N₆ • H₂O
658452 AG 126 - CAS 118409-62-4 - Calbiochem A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-α and nitric oxide in murine peritoneal macrophages. C₁₀H₅N₃O₃
662005 U0126 - CAS 109511-58-2 - Calbiochem U0126, CAS 109511-58-2, is a potent and specific inhibitor of MEK1 (IC₅₀ = 72 nM) and MEK2 (IC₅₀ = 58 nM). The inhibition is noncompetitive with respect to both ATP and ERK. C₁₈H₁₆N₆S₂•½C₂H₅OH
662006 U0124 - CAS 1140528-25-1 - Calbiochem A useful negative control for MEK inhibitors U0125 and U0126. C₈H₁₀N₄S₂
662009 InSolution™ U0126 - CAS 109511-58-2 - Calbiochem A potent and specific inhibitor of MEK1 and MEK2 . C₁₈H₁₆N₆S₂•½C₂H₅OH
692000 ZM 336372 - CAS 208260-29-1 - Calbiochem A potent, cell-permeable, reversible, ATP-competitive and specific inhibitor of the protein kinase c-Raf (IC₅₀ = 70 nM). C₂₃H₂₃N₃O₃
SMB00446 Peimine ≥98% (HPLC) C27H45NO3
S8307 SB 203580 solid, ≥98% (HPLC) C21H16FN3OS