Building Blocks for HIV Protease Inhibitors

Protease inhibitors are an important class of totally synthetic drugs for the treatment of HIV. They are "peptoids" or "peptido-mimetics" (similar to peptides) that bind and block the active site of the proteinase enzyme necessary for HIV replication, thus stopping the AIDS virus from developing. The complexity of protease inhibitors has generated much effort toward the efficient synthesis of intermediates used in their preparation.

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Molecular Formula

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440841 (1R,2S)-(+)-cis-1-Amino-2-indanol 99% C9H11NO
440833 (1S,2R)-(−)-cis-1-Amino-2-indanol 99% C9H11NO
469289 N-Boc-D-phenylalaninal 97% C14H19NO3
469297 N-Boc-L-phenylalaninal 97% C14H19NO3
468916 [3S-(3α,4aβ,8aβ)]-N-(tert-Butyl)decahydro-3-isoquinolinecarboxamide 98% C14H26N2O
421731 (S)-(+)-2-(Dibenzylamino)-3-phenyl-1-propanol 99% C23H25NO
476951 (2S,3S)-1,2-Epoxy-3-(Boc-amino)-4-phenylbutane 99% C15H21NO3
309753 (R)-(−)-3-Hydroxytetrahydrofuran 98% C4H8O2
296686 (S)-(+)-3-Hydroxytetrahydrofuran 99% C4H8O2
459933 Z-D-Phenylalaninol 97% C17H19NO3