Antibodies to Nucleus

The nucleus is a membrane-enclosed organelle found in eukaryotic cells that contains the genetic information of the cell. The function of the nucleus is to maintain the integrity of the genes and to control the activities of the cell by regulating gene expression. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm. The interior of the nucleus does not contain any membrane-bound sub compartments, its contents are not uniform, and a number of sub-nuclear bodies exist, made up of specific subset of proteins and RNA. The best-known of these is the nucleolus, which is mainly involved in rDNA transcription and ribosome biosynthesis.
IF staining of nucleus and nuclear membrane in HeLa cells using Anti-LAP2 (TMPO), clone 6E1
IF staining of nuclear membrane in HeLa cells using Anti-Lamin A (C-terminal) (L1293