Antibodies to Microtubule and Associated Proteins

Sigma® Life Science offers a large selection of tubulin antibodies and associated proteins. Select appropriate tubulin antibodies for your research by form, gene symbol, species reactivity or application. Each tubulin antibody is covered by our Bioguarantee so that you can evaluate our antibodies with complete peace of mind.

Microtubules of the eukaryotic cytoskeleton are composed of a heterodimer of a- and ß-tubulin. In addition to a-and ß-tubulin, several other tubulins have been identified, bringing the number of distinct tubulin classes to seven. Most of these tubulins have distinct subcellular localization and an emerging, diverse set of functions. Out of the seven different tubulins four new members of the tubulin family were identified recently, which consist of δ, χ, η, and ε-tubulin. η and ε-tubulins were discovered by database searches.

ε-Tubulin is located in the pericentriolar area, and its localization is modulated by cell cycle progression. During the early phase of the cell cycle, the protein associates predominantly with the old centrosome, and only later does it become associated with both the old and the new centrosomes. Centrosomes can initiate microtubule assembly irrespective of e-tubulin content, indicating that this protein is not involved in microtubule nucleation.

A unique Monoclonal Antibody to ε-Tubulin, clone TUB-11 is directed against the C-terminal region of ε-tubulin (amino acids 352-366 of human ε-tubulin) and may be used in ELISA and immunoblotting. The antibodies provide specific and useful tools for studying the intracellular distribution and cell cycle-dependent expression of ε-tubulin.

The innovative Monoclonal Anti-e-Tubulin antibody complements our wide selection of antibodies to different tubulins, which include antibodies to α, ß, and γ-tubulins, as well as antibodies to modified tubulins, such as acetylated-tubulin, tyrosine-tubulin and polyglutamylated tubulin.

References
Dutcher, S.K., et al. Curr. Opin. Cell Biol., 13, 49-54 (2001).
McKean, P.G., et al. J. Cell Sci., 114, 2723-2733 (2001).
Chang, P., Stearns, T. Nature Cell Biol., 2, 30-35 (2000).

Product #

Description

Clone

Application

Species Reactivity

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C7736 Anti-Centrin antibody produced in rabbit polyclonal
ARR, WB human
WH0001068M1 Monoclonal Anti-CETN1 antibody produced in mouse 2A6, monoclonal
ELISA (i), WB human
HPA021649 Anti-DNAI1 antibody produced in rabbit Antibody Enhanced Validation polyclonal
IHC human
HPA021843 Anti-DNAI1 antibody produced in rabbit Antibody Enhanced Validation polyclonal
IHC human
WH0027019M1 Monoclonal Anti-DNAI1 antibody produced in mouse 2D10-2A5, monoclonal
ELISA (i), WB human
WH0064446M1 Monoclonal Anti-DNAI2 antibody produced in mouse 1C8, monoclonal
ELISA (i), IF, WB human
D1667 Monoclonal Anti-Dynein (Heavy Chain) antibody produced in mouse 440.4, monoclonal
ELISA (i), WB human, chicken
D5167 Monoclonal Anti-Dynein (Intermediate Chain) antibody produced in mouse 70.1, monoclonal
ELISA (i), IP, WB chicken, rat, hamster, marsupial, Indian muntjac (Muntiacus muntjac vaginalis), frog, human
D9944 Monoclonal Anti-DYNLT1 antibody produced in mouse T1, monoclonal
ICC, WB mouse, human, bovine, rat, monkey
HPA003938 Anti-DYNLT3 antibody produced in rabbit Antibody Enhanced Validation polyclonal
IHC rat, human
D2820 Monoclonal Anti-DYNLT3 antibody produced in mouse R1, monoclonal
IP, WB human, rat
K1390 Monoclonal Anti-hKid antibody produced in mouse 8C12, monoclonal
ELISA (i), ICC, IP, WB human
K3638 Anti-KIF17 antibody produced in rabbit polyclonal
ARR, IF, WB rat, mouse
AV33920 Anti-KIF22 antibody produced in rabbit polyclonal
WB human
K3513 Anti-KIF3A antibody produced in rabbit polyclonal
ARR, IHC (p), WB human, rat, mouse
SAB2500560 Anti-KIF4A antibody produced in goat polyclonal
ELISA (i), IF rat, human, mouse
 
M4278 Monoclonal Anti-MAP1 antibody produced in mouse HM-1, monoclonal
ARR, IHC (f), WB rat, mouse
HPA022275 Anti-MAP1B antibody produced in rabbit Antibody Enhanced Validation polyclonal
IF, IHC, WB human
M4528 Monoclonal Anti-MAP1b antibody produced in mouse AA6, monoclonal
ARR, WB chicken, bovine, human, mouse, hamster, rat, feline
M3696 Anti-MAP2 antibody produced in rabbit polyclonal
FACS, IHC, WB rat, human, mouse
 
HPA008273 Anti-MAP2 antibody produced in rabbit Antibody Enhanced Validation polyclonal
IF, IHC human
HPA012828 Anti-MAP2 antibody produced in rabbit polyclonal
IF, IHC human
M4403 Monoclonal Anti-MAP2 antibody produced in mouse HM-2, monoclonal
IHC (p), WB rat, mouse, chicken, human, bovine, quail
M1406 Monoclonal Anti-MAP2 (2a+2b) antibody produced in mouse AP-20, monoclonal
ICC, WB Xenopus, bovine, human, mouse, rat, aquatic salamander, quail
M2320 Monoclonal Anti-MAP2 (2a+2b) antibody produced in mouse AP-20, monoclonal
ARR, ICC, WB Xenopus, bovine, human, mouse, rat, aquatic salamander, quail
M9942 Anti-MAP2 antibody, Mouse Monoclonal HM-2, monoclonal
ARR, ICC, IHC, WB rat, mouse, chicken, human, bovine, quail
AV48103 Anti-MAPT antibody produced in rabbit polyclonal
IHC, WB human
M7273 Anti-Microtubule-Associated Proteins (MAPs) antibody produced in rabbit polyclonal
WB mammals
 
SAB4200171 Anti-NEZHA (C-terminal) antibody produced in rabbit polyclonal
IF, IP, WB human
PRS4235 Anti-Op18 (ab1) antibody produced in rabbit polyclonal
ELISA (i), IF, IHC, WB human, mouse
PRS4237 Anti-Op18 (ab2) antibody produced in rabbit polyclonal
ELISA (i), IF, IHC, WB human, mouse, rat
P9318 Monoclonal Anti-Plectin antibody produced in mouse 7A8, monoclonal
ARR, DB, ELISA (i), ICC, IF, IHC (f), WB marsupial (Ptoorous tridactylis PtK2 cell line), rat
HPA017311 Anti-SPAST antibody produced in rabbit polyclonal
IF, IHC rat, human
WH0006683M1 Monoclonal Anti-SPAST antibody produced in mouse 3A12, monoclonal
ELISA (i), WB human
WH0003925M1 Monoclonal Anti-STMN1 antibody produced in mouse 3A9, monoclonal
ELISA (i), IP, WB human
SAB2500996 Anti-STMN1/STATHMIN 1 antibody produced in goat polyclonal
ELISA (i), WB rat, human, mouse
T6402 Anti-τ (Tau) antibody produced in rabbit polyclonal
WB rat, chicken, mouse
T5530 Monoclonal Anti-τ (Tau) antibody produced in mouse TAU-2, monoclonal
ARR, IHC (p), WB bovine, chicken, human, monkey
 
T9450 Anti-Tau antibody, Mouse monoclonal Tau46, monoclonal
ARR, ELISA (i), IHC, IP, WB bovine, rat, human, mouse
T8444 Anti-phospho-Tau (pSer199) antibody produced in rabbit polyclonal
WB rat, mouse, human
 
T6819 Anti-phospho-Tau (pSer199/202) antibody produced in rabbit polyclonal
ARR, WB mouse, rat, human
 
T7569 Anti-phospho-Tau (pSer262) antibody produced in rabbit polyclonal
WB human, mouse, rat
 
T7319 Anti-phospho-Tau (pSer396) antibody produced in rabbit polyclonal
WB rat, mouse, human
 
T7444 Anti-phospho-Tau (pSer404) antibody produced in rabbit polyclonal
IHC, WB mouse, human, rat
 
T6694 Anti-phospho-Tau (pThr205) antibody produced in rabbit polyclonal
IHC, WB mouse, rat, human
 
HPA018113 Anti-TTBK2 antibody produced in rabbit Antibody Enhanced Validation polyclonal
IHC, WB human
WH0007277M1 Monoclonal Anti-TUBA1 antibody produced in mouse 2E11, monoclonal
ELISA (i), IF, IHC (p), WB human
SAB2102603 Anti-TUBA4A antibody produced in rabbit polyclonal
IHC, IP, WB mouse, horse, rat, dog, human, sheep, guinea pig, bovine, rabbit
WH0203068M4 Monoclonal Anti-TUBB antibody produced in mouse 3B3, monoclonal
ELISA (i), WB human
GW21263 Anti-TUBB2A antibody produced in chicken polyclonal
WB mouse, human, rat
 
WH0010383M2 Monoclonal Anti-TUBB2C antibody produced in mouse 1G3, monoclonal
ELISA (i), IF, WB human
SAB3300047 Monoclonal Anti-TUBB3 antibody produced in mouse 5H2, monoclonal
WB human
 
HPA023980 Anti-TUBD1 antibody produced in rabbit polyclonal
IF, IHC human
HPA027090 Anti-TUBD1 antibody produced in rabbit polyclonal
IF, IHC human
SAB1401679 Monoclonal Anti-TUBD1 antibody produced in mouse 3C7, monoclonal
ELISA (c), IP human
HPA032073 Anti-TUBE1 antibody produced in rabbit polyclonal
IHC human
HPA032074 Anti-TUBE1 antibody produced in rabbit polyclonal
IHC human
SAB1401680 Anti-TUBE1 antibody produced in rabbit polyclonal
WB human
WH0027175M1 Monoclonal Anti-TUBG2 antibody produced in mouse 4F6, monoclonal
ELISA (i), IF, WB human
T6793 Monoclonal Anti-Tubulin, Acetylated antibody produced in mouse 6-11B-1, monoclonal
DB, ELISA (i), EM, ICC, RIA, WB mouse, rat, chicken, protista, bovine, invertebrates, human, monkey, pig, frog, plant, hamster
T7451 Monoclonal Anti-Acetylated Tubulin antibody produced in mouse 6-11B-1, monoclonal
DB, EM, IHC, RIA, WB plant, hamster, rat, mouse, human, pig, monkey, frog, invertebrates, bovine, protista, chicken
T3526 Anti-Tubulin antibody produced in rabbit polyclonal
IF, WB chicken, mouse
SAB3500023 Anti-α-Tubulin from chicken polyclonal
ELISA (i), WB rat, human, mouse
T5192 Anti-γ-Tubulin antibody produced in rabbit polyclonal
IF, WB chicken, human
T3559 Anti-γ-Tubulin antibody produced in rabbit polyclonal
ARR, IF, WB chicken, human
C4585 Monoclonal Anti-β-Tubulin−Cy3 antibody produced in mouse TUB 2.1, monoclonal
IF (d) wheat, mouse, hamster, sea urchin, frog, plant, bovine, rat, rabbit, moth, chicken, human
F2043 Monoclonal Anti-β-Tubulin−FITC antibody produced in mouse TUB 2.1, monoclonal
IF (d) wheat, mouse, hamster, sea urchin, frog, plant, bovine, rat, rabbit, moth, chicken, human
T8535 Monoclonal Anti-β-Tubulin I+II antibody produced in mouse JDR.3B8, monoclonal
ARR, ELISA (i), IF, WB human, chicken, mouse, rat, bovine, pig
T2200 Anti-β-Tubulin III antibody produced in rabbit Antibody Enhanced Validation polyclonal
IF, IP, WB human, rat, mouse
T3952 Anti-β-Tubulin III antibody produced in rabbit polyclonal
WB human
 
T8660 Monoclonal Anti-β-Tubulin III antibody produced in mouse Antibody Enhanced Validation SDL.3D10, monoclonal
ELISA (i), WB bovine, boar, rat, human
T8578 Monoclonal Anti-β-Tubulin III (neuronal) antibody produced in mouse 2G10, monoclonal
ICC, IHC, IP, WB human, rat, mouse
T5076 Monoclonal Anti-β-Tubulin Isotype III antibody produced in mouse SDL.3D10, monoclonal
ARR, DB, ELISA (i), ICC, IHC, WB human, bovine, mouse, rat, boar
T7941 Monoclonal Anti-β-Tubulin IV antibody produced in mouse ONS.1A6, monoclonal
ARR, ELISA (i), IHC (p), WB rat, human, hamster, chicken, mouse, bovine
T3320 Anti-γ-Tubulin (AK-15) antibody produced in rabbit polyclonal
ARR, ICC, WB rat, human, frog
C7604 Anti-γ-Tubulin-Cy3 antibody produced in rabbit polyclonal
IF (d) chicken, human
T3195 Anti-γ-Tubulin (DQ-19) antibody produced in rabbit polyclonal
IF, WB chicken, human
T1450 Anti-γ-Tubulin (LL-17) antibody produced in rabbit polyclonal
WB Caenorhabditis elegans
T5168 Monoclonal Anti-α-Tubulin antibody produced in mouse Antibody Enhanced Validation B-5-1-2, monoclonal
IF, RIA, WB chicken, kangaroo rat, sea urchin, rat, Chlamydomonas, bovine, human, African green monkey, mouse
T9026 Monoclonal Anti-α-Tubulin antibody produced in mouse Antibody Enhanced Validation DM1A, monoclonal
IF, WB bovine, rat, yeast, human, mouse, chicken, fungi, amphibian
T6074 Monoclonal Anti-α-Tubulin antibody produced in mouse Antibody Enhanced Validation B-5-1-2, monoclonal
ARR, ICC, IP, WB chicken, kangaroo rat, sea urchin, rat, Chlamydomonas, bovine, human, African green monkey, mouse
T4026 Monoclonal Anti-β-Tubulin antibody produced in mouse Antibody Enhanced Validation TUB 2.1, monoclonal
IF, WB wheat, mouse, hamster, sea urchin, frog, plant, bovine, rat, rabbit, moth, chicken, human
T8328 Monoclonal Anti-β-Tubulin antibody produced in mouse AA2, monoclonal
ICC, IHC, IP, WB rat, human, mouse, bovine
T5201 Monoclonal Anti-β-Tubulin antibody produced in mouse TUB 2.1, monoclonal
ARR, IEP, IF, IHC, WB wheat, mouse, hamster, sea urchin, frog, plant, bovine, rat, rabbit, moth, chicken, human
T0198 Monoclonal Anti-β-Tubulin antibody produced in mouse D66, monoclonal
ELISA (i), ICC, IP, WB monkey, Oxyrrhis marina (dinoflagellate), rat, mouse, chicken, sea urchin (Lytechinus pictus and Paracentrotus lividus), rabbit, canine, Chlamydomonas reinhardtii, human, bovine, hamster
T5293 Monoclonal Anti-β-Tubulin antibody produced in mouse Antibody Enhanced Validation 2-28-33, monoclonal
IF, WB bovine, chicken, Strongylocentrotus purpuratus, rat, Ciona intestinalis, Caenorhabditis elegans, human
T7816 Monoclonal Anti-β-Tubulin I antibody produced in mouse SAP.4G5, monoclonal
ARR, ELISA (i), ICC, IHC (p), WB canine, bovine, human, hamster, chicken, Xenopus, rat, mouse
T6557 Monoclonal Anti-γ-Tubulin antibody produced in mouse GTU-88, monoclonal
ELISA (i), ICC, WB bovine, mouse, rat, chicken, Xenopus, human, hamster, canine
T5326 Monoclonal Anti-γ-Tubulin antibody produced in mouse GTU-88, monoclonal
ARR, ELISA (i), ICC, IP, WB bovine, mouse, rat, chicken, Xenopus, human, hamster, canine
T1323 Monoclonal Anti-ε-Tubulin antibody produced in mouse TUB-11, monoclonal
ARR, ELISA (i), IHC, WB human, mouse, chicken, frog
T9822 Monoclonal Anti-Tubulin, Polyglutamylated antibody produced in mouse B3, monoclonal
ARR, ELISA (i), ICC, WB rabbit, rat, chicken, mouse, bovine, human, Oxyrrhis marina (dinoflagellate), monkey, sea urchin (Lytechinus pictus and three others.)
T9028 Monoclonal Anti-Tubulin, Tyrosine antibody produced in mouse TUB-1A2, monoclonal
ARR, IF, WB plant, human, animal
T6199 Anti-α-Tubulin antibody, Mouse monoclonal Antibody Enhanced Validation DM1A, monoclonal
ARR, ICC, IHC, IP, WB bovine, rat, yeast, human, mouse, chicken, fungi, amphibian
T8203 Anti-α-Tubulin antibody, Mouse monoclonal AA13, monoclonal
ELISA (i), ICC, IHC, IP, WB human, mouse, rat
F2168 Anti-α-Tubulin−FITC antibody, Mouse monoclonal DM1A, monoclonal
IF (d) bovine, rat, yeast, human, mouse, chicken, fungi, amphibian
T8453 Anti-β-Tubulin II antibody, Mouse monoclonal 7B9, monoclonal
ICC, IP, WB rat, human, mouse
T0950 Anti-γ-Tubulin (QG-17) antibody produced in rabbit polyclonal
WB Drosophila