DISCOVER Bioactive Small Molecules

We understand that in your research, the right tools are essential to ensuring that your target is the right target. With more than 4,000 Bioactive Small Molecules for almost any pathway and all major target classes, we are the premier destination for potent, selective tools for target identification and validation.

DISCOVER the right small molecules for your research

The extensive Bioactive Small Molecule portfolio offers inhibitors, receptor ligands, pharma-developed tools and approved drugs for most signaling pathways and all major drug classes. To discover some of the featured bioactive small molecules for your area of research, click on the categories below.

DISCOVER Enhanced access to Pfizer compounds

The research community has enhanced access to authentic, high-quality Pfizer compounds through our catalog. To further research in drug discovery, over 175 authentic, quality-controlled Pfizer probes and drugs compounds are available for multiple research areas, fostering reproducibility, innovation, and discovery. To learn more about our partnership with Pfizer and to view Pfizer compounds for your area of research, visit our Pfizer compounds page.

 Additional Resources

Bioactive Small Molecules
Explore the full offering of the Bioactive Small Molecule portfolio, including LOPAC® and Pfizer compounds, and find additional resources for your reference.


New Small Molecule
New small molecules products are added to the portfolio weekly. Browse the newly launched molecules by area of research.


Browse the eHandbook
Over 100 peer-reviewed entries in the Handbook of Receptor Classification and Signal Transduction covering topics such as GPCRs, Ion Channels, and more as well as links to hundreds of related small molecules.


SGC Epigenetic Probes
We have partnered with the Structural Genomics Consortium (SGC) to provide novel chemical probes for epigenetic research. Click here to learn more.
Learn more about the LOPAC library of high quality, ready to screen compounds for target characterization and assay validation.
Pharma-developed Compounds
Over 800 pharma-developed approved therapeutics and drug candidates are available in our catalog. Find your molecule of interest here.