Vascular Endothelial Growth Factor (VEGF)/KDR

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H4914 Honokiol ≥98% (HPLC), powder Honokiol is a natural biphenyl neolignan from magnolia extract. It is antiangiogenic, antitumor, and anxiolytic.
SML1164 SKLB1002 ≥98% (HPLC) SKLB1002 is a cell permeable and potent VEGFR2 inhibitor that potently inhibits HUVEC cells proliferation, migration, invasion, and tube formation. It appears that SKLB1002 inhibits VEGF-induced phosphorylation of VEGFR2 kinase and the downstream protein kinases including extracellular signal regulated kinase, focal adhesion kinase, and Src. SKLB1002 inhibits angiogenesis.