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G113 GR 64349 >96% GR 64349 peptide acts as an agonist of neurokinin (NK2) receptor, which leads to reduced NK2 response to kainate and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), but not to NMDA (N-methyl-D-aspartate).
G114 GR 73632 >97% GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.
S2136 [Met-OH11]-Substance P ≥97% (HPLC) NK-1 agonist
N4267 Neurokinin A ≥97% (HPLC) Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.
N4143 Neurokinin B ≥95% (HPLC) Neurokinin B is a ten-residue peptide. It is an endogenous tachykinin agonist with preference for the NK-3 receptor. It is a potent bronchoconstrictor and may have a neuromodulatory role in the brain. Neurokinin B has a role in slow synaptic or non-synaptic communication.
S6883 Substance P acetate salt hydrate ≥95% (HPLC), powder NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents.
S3672 [Sar9, Met(O2)11]-Substance P ≥95% (HPLC) Highly selective NK-1 receptor agonist.
S6272 Substance P Fragment 1-7 ≥97% (HPLC) Fragment that gives depressor and bradycardic effects when applied to the nucleus tractus solitarius
S2275 Acetyl-[Arg6, Sar9, Met(O2)11]-Substance P Fragment 6-11 ≥95% Selective NK-1 receptor agonist.