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G113 GR 64349 >96% GR 64349 peptide acts as an agonist of neurokinin (NK2) receptor, which leads to reduced NK2 response to kainate and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), but not to NMDA (N-methyl-D-aspartate).
N4267 Neurokinin A ≥97% (HPLC) Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.
N4143 Neurokinin B ≥95% (HPLC) Neurokinin B is a ten-residue peptide. It is an endogenous tachykinin agonist with preference for the NK-3 receptor. It is a potent bronchoconstrictor and may have a neuromodulatory role in the brain. Neurokinin B has a role in slow synaptic or non-synaptic communication.
S6883 Substance P acetate salt hydrate ≥95% (HPLC), powder NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents.
Substance P has proinflammatory effects on epithelial and immune cells. It has been associated with inflammatory diseases related to gastrointestinal and respiratory systems. Substance P modulates contractility of smooth muscles, transport of ions in the epithelium, vascular permeability and immune functions in the gut.
S3672 [Sar9, Met(O2)11]-Substance P ≥95% (HPLC) Highly selective NK-1 receptor agonist.
S6272 Substance P Fragment 1-7 ≥97% (HPLC) Fragment that gives depressor and bradycardic effects when applied to the nucleus tractus solitarius
S2275 Acetyl-[Arg6, Sar9, Met(O2)11]-Substance P Fragment 6-11 ≥95% Selective NK-1 receptor agonist.