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SML0752 (+)-CP-99994 dihydrochloride ≥98% (HPLC) (+)-CP-99994 dihydrochloride is an effective and selective non-peptide substance P receptor antagonist. It is synthesized from allylic and homoallylic C-H diamination of 4-phenyl-1-butene. (+)-CP-99994 exhibits anti-emetic activity in ferrets.
(+)-CP-99994 is a selective neurokinin (NK)-1 tachykinin antagonist. (+)-CP-99994 binds selectively and with high affinity with a Ki of 0.25 nM in a human cell line.
H0409 Hylambatin >96% (HPLC) Tachykinin that increases plasma glucose and plasma insulin.