Guanylate Cyclase Activators

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Biochem/physiol Actions

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A1663 Atrial Natriuretic Peptide human ≥97% (HPLC) Atrial natriuretic peptide (ANP) is synthesized in myoendocrine cells of the heart from which it is released into the circulation. It exerts natriuretic, diuretic, and vasodilatory effects through stimulation of guanylate cyclase-linked NPR-A receptors. It plays an important role in blood volume and blood pressure homeostasis.
A9035 Atriopeptin II rat Activates particulate guanylyl cyclase; cardiac atrial peptide which relaxes both intestinal and vascular smooth muscle.
U5131 Uroguanylin ≥90% (HPLC) Stimulates intestinal guanylate cyclase.