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M5644 (±)-Methoxyverapamil hydrochloride ≥98% Blocks L-type Ca2+ channels
V108 (±)-Norverapamil hydrochloride ≥98% (HPLC) (±)-Norverapamil is a Ca2+ channel (L-type) antagonist; N-demethylated metabolite of verapamil.
V4629 (±)-Verapamil hydrochloride ≥99% (titration), powder α1-adrenoceptor antagonist; L-type calcium channel blocker. Blocks L-type Ca2+ channels in smooth and cardiac muscle, induces apoptosis of human primary and metastatic colon adenocarcinoma cells in vitro. Drug resistance reversal agent acting on Pgp, e.g. decrease renal tubule elimination of digoxin. Increases basal ATPase activity of Pgp. Substrate of Cyp3A4 and CYP2C6.
V105 S(−)-Verapamil hydrochloride hydrate ≥98% (HPLC), powder Active enantiomer of (±)-verapamil. Ca2+ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant.