Other Dopaminergics

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M0896 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride powder Dopaminergic neurotoxin.
M103 1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride solid Dopaminergic neurotoxin that is more toxic in mice than MPTP.
850217 3,4-Dihydroxyphenylacetic acid 98%  
D9378 3,4-Dihydroxy-D-phenylalanine powder, ≥95% DOPA enantiomer that lacks biological activity.
D9503 3,4-Dihydroxy-DL-phenylalanine Immediate precursor of dopamine; product of tyrosine hydroxylase
D9628 3,4-Dihydroxy-L-phenylalanine ≥98% (TLC) 3,4-Dihydroxy-L-phenylalanine or L-DOPA is a natural isomer of the immediate precursor of dopamine that crosses the blood-brain barrier. It is used for the treatment of Parkinson’s disease and is a product of tyrosine hydroxylase.
H3132 3-Hydroxy-4-methoxyphenethylamine hydrochloride Dopamine metabolite.
M4251 3-Methoxytyramine hydrochloride ≥95.5%, crystalline Major metabolite of dopamine; product of catechol O-methyltransferase.
C156 D-CPT tartrate >94%, solid Binds to the cocaine receptor site on the dopamine transporter and blocks dopamine uptake.
855456 D-Tyrosine ReagentPlus®, 99%  
D1507 L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride solid Precursor to L-DOPA that crosses the blood-brain barrier; antiparkinsonian agent.
T2269 L-Tyrosine disodium salt hydrate ≥98% (HPLC), powder  
T2006 L-Tyrosine hydrochloride ≥98% (TLC)  
T3754 L-Tyrosine reagent grade, ≥98% (HPLC) L-Tyrosine is a non-essential amino acid with a polar side chain. It is utilized by cells to synthesize proteins that have a role in signal transduction. L-Tyrosine is a proteogenic amino acid that acts as a receiver of phosphate groups that are transferred by kinases.
A1260 Amantadine hydrochloride Dopamine releaser used to treat Parkinsonism and drug-induced extrapyramidal reactions.
H1252 Homovanillic acid Fluorimetric reagent Metabolite of dihydroxyphenylacetic acid (DOPAC) by catechol O-methyltransferase; reagent for the fluorimetric determination of glucose oxidase and other oxidative enzymes.
SML0756   IDT307 ≥98% (HPLC) IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+ monoamine transporter substrate that fluoresces after uptake into cells. IDT307 is a substrate for the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). IDT307 (APP+) was found to label catecholamine neuronal cell bodies with high selectivity in midbrain and was used to investigate SERT function in lymphocytes and platelets.
SML0091 L-Dopa ethyl ester ≥98% (HPLC) L-Dopa ethyl ester (L-Dopa) is a dopamine replacement drug. It is used as a potent therapeutic for Parkinson disease (PD). L-Dopa has some long-term side effects, such as the deterioration of motor function.
L-Dopa ethyl ester is a prodrug of levodopa that has greater gastric solubility. The drug is rapidly hydrolyzed to levodopa by nonspecific esterases in the gastrointestinal tract. L-Dopa ethyl ester (etilevodopa)-carbidopa treatment was well tolerated but did not demonstrate better efficacy compared with standard levodopa-carbidopa treatment. L-Dopa ethyl ester should have a significant brain penetration following an administration by injection.
D048 MPP+ iodide ≥98% (HPLC), powder MPP+ iodide is an active metabolite of dopaminergic neurotoxin MPTP.
P0099 Paliperidone ≥98% (HPLC) Paliperidone is an atypical antipsychotic; active metabolite of risperidone.
R0875 Reserpine Inhibits vesicular uptake of catecholamines and serotonin.
D204 S-(+)-O-Desmethylraclopride hydrobromide solid, ≥98% (HPLC)  
S4326 SB-277011-A hydrochloride hydrate ≥98% (HPLC) SB-277011-A is a potent, selective brain-penetrant D3 dopamine receptor antagonist; 80-100x selective for D3 over D2; pKi = 7.95 for hD3 receptor.
The D3 dopamine receptor antagonist, SB-277011-A inhibits the cocaine-seeking behavior and cocaine-enhances brain stimulation reward in in rats. It decreases drug-seeking behavior and may be useful in treatment of cocaine and methamphetamine addiction.
T2952 Tetrabenazine ≥98% (HPLC), solid Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor. It depletes dopamine stores.