Other Dopaminergics

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M0896 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride powder Dopaminergic neurotoxin.
M103 1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride solid Dopaminergic neurotoxin that is more toxic in mice than MPTP.
850217 3,4-Dihydroxyphenylacetic acid 98%  
D9378 3,4-Dihydroxy-D-phenylalanine powder, ≥95% DOPA enantiomer that lacks biological activity.
D9503 3,4-Dihydroxy-DL-phenylalanine 3,4-dihydroxyphenylalanine is an immediate precursor of dopamine, which is a product of tyrosine hydroxylase.
D9628 3,4-Dihydroxy-L-phenylalanine ≥98% (TLC) 3,4-Dihydroxy-L-phenylalanine or L-DOPA is a natural isomer of the immediate precursor of dopamine that crosses the blood-brain barrier. It is used for the treatment of Parkinson’s disease and is a product of tyrosine hydroxylase.
H3132 3-Hydroxy-4-methoxyphenethylamine hydrochloride Dopamine metabolite.
M4251 3-Methoxytyramine hydrochloride ≥95.5%, crystalline Major metabolite of dopamine; product of catechol O-methyltransferase.
C156 D-CPT tartrate >94%, solid Binds to the cocaine receptor site on the dopamine transporter and blocks dopamine uptake.
855456 D-Tyrosine ReagentPlus®, 99%  
D1507 L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride solid L-3,4-Dihydroxyphenylalanine methyl ester is a precursor to L-DOPA that crosses the blood-brain barrier. Antiparkinsonian agent L-DOPA methyl ester elicits antitumor functionality in leukemia and melanoma.
T2269 L-Tyrosine disodium salt hydrate ≥98% (HPLC), powder  
T2006 L-Tyrosine hydrochloride ≥98% (TLC) Tyrosine is a nonessential amino acid found in mammal, fish and birds. It participates in protein modification, such as phosphorylation, nitrosation and sulfation. It is involved in immune response regulation and prevents the generation of inflammatory cytokines and superoxide. Tyrosine serves as a precursor for epinephrine, norepinephrine, dopamine, thyroid hormones and melanin biosynthesis. Tyrosine phosphorylation is associated with a number of cellular processes such as cell proliferation and migration, development of the embryo, cellular metabolism and transcription. Tyrosine phosphorylation also aids activation of the enzymatic function of a protein.
T3754 L-Tyrosine reagent grade, ≥98% (HPLC) L-Tyrosine is a non-essential amino acid with a polar side chain. It is utilized by cells to synthesize proteins that have a role in signal transduction. L-Tyrosine is a proteogenic amino acid that acts as a receiver of phosphate groups that are transferred by kinases.
A1260 Amantadine hydrochloride Dopamine releaser used to treat Parkinsonism and drug-induced extrapyramidal reactions.
D4446   Dopamine D1 Receptor human recombinant, expressed in HEK 293 cells, membrane suspension Membranes are suspended in 50 mM TRIS-HCl containing 10 mM MgCl2, 1.5 mM CaCl2, 1mM EDTA, 5 mM KCl, 10% glycerol, (pH 7.4 at 25 °C).
H1252 Homovanillic acid Fluorimetric reagent Metabolite of dihydroxyphenylacetic acid (DOPAC) by catechol O-methyltransferase; reagent for the fluorimetric determination of glucose oxidase and other oxidative enzymes.
SML0756   IDT307 ≥98% (HPLC) IDT307 (APP+) is a fluorescent analogue of the dopaminergic neurotoxin MPP+ monoamine transporter substrate that fluoresces after uptake into cells. IDT307 is a substrate for the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). IDT307 (APP+) was found to label catecholamine neuronal cell bodies with high selectivity in midbrain and was used to investigate SERT function in lymphocytes and platelets.
SML0091 L-Dopa ethyl ester ≥98% (HPLC) L-Dopa ethyl ester (L-Dopa) is a dopamine replacement drug. It is used as a potent therapeutic for Parkinson disease (PD). L-Dopa has some long-term side effects, such as the deterioration of motor function.
L-Dopa ethyl ester is a prodrug of levodopa that has greater gastric solubility. The drug is rapidly hydrolyzed to levodopa by nonspecific esterases in the gastrointestinal tract. L-Dopa ethyl ester (etilevodopa)-carbidopa treatment was well tolerated but did not demonstrate better efficacy compared with standard levodopa-carbidopa treatment. L-Dopa ethyl ester should have a significant brain penetration following an administration by injection.
D048 MPP+ iodide ≥98% (HPLC), powder MPP+ iodide is an active metabolite of dopaminergic neurotoxin MPTP.
P0099 Paliperidone ≥98% (HPLC) Paliperidone is an atypical antipsychotic; active metabolite of risperidone.
R0875 Reserpine Inhibits vesicular uptake of catecholamines and serotonin.
Reserpine is an alkaloid present in Rauwolfia species. It is useful in treating systemic hypertension, schizophrenia, psychiatric disorders and Raynaud′s syndrome. Reserpine is known to inhibit adrenaline induced-cutaneous blood vessel constriction. It diminishes the effect of hyperthyroidism on cardiovascular and nervous system.
D204 S-(+)-O-Desmethylraclopride hydrobromide solid, ≥98% (HPLC)  
S4326 SB-277011-A hydrochloride hydrate ≥98% (HPLC) SB-277011-A is a potent, selective brain-penetrant D3 dopamine receptor antagonist; 80-100x selective for D3 over D2; pKi = 7.95 for hD3 receptor.
The D3 dopamine receptor antagonist, SB-277011-A inhibits the cocaine-seeking behavior and cocaine-enhances brain stimulation reward in in rats. It decreases drug-seeking behavior and may be useful in treatment of cocaine and methamphetamine addiction.
T2952 Tetrabenazine ≥98% (HPLC), solid Tetrabenazine is a reversible type 2 vesicular monoamine transporter (VMAT) inhibitor. It depletes dopamine stores.