Progesterone is a steroid hormone involved in the female menstrual cycle, pregnancy, and the embryonic development of humans and other species. Progesterone belongs to a class of hormones called progestogens. This steroid hormone is produced in the ovaries, the adrenal glands, and in the placenta during pregnancy. Progesterone, like all steroids, is a small hydrophobic molecule that diffuses freely through the plasma membrane of target cells. Progesterone, in combination with a high estrogen level, suppresses further ovulation during pregnancy and also encourages the growth of milk-producing glands in the breast during pregnancy. Progesterone is stored in adipose tissue and also plays a role in sexual desire. It is derived from cholesterol, and is the precursor of the male sex hormones aldosterone, androstenedione, and cortisol.

To further understand the role of progesterone and its physiological effects on the body, Sigma-Aldrich offers a variety of products including hormones, hormone precursors, and progesterone receptor antagonists.

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A1487 AG-205 ≥98% (HPLC)
SML1468 Dienogest ≥98% (HPLC)
SML0147 Drospirenone ≥98% (HPLC)
SML0356 Etonogestrel ≥98% (HPLC)
SML0292 Gestodene ≥98% (HPLC)
H5752 17α-Hydroxyprogesterone ≥95%
D6875 21-Hydroxyprogesterone ≥97% (HPLC)
M6013 Medroxyprogesterone
M1629 Medroxyprogesterone 17-acetate ≥97% (HPLC)
M0388 6α-Methyl-11β-hydroxyprogesterone
SML0550 Nestorone ≥97% (HPLC)
SML0359 Norgestimate ≥97% (HPLC)
P0130 Progesterone ≥99%
P8783 Progesterone powder, BioReagent, suitable for cell culture
P6149 Progesterone γ-irradiated, BioXtra, suitable for cell culture
P1922 Monoclonal Anti-Progesterone antibody produced in rat clone 2H4, tissue culture supernatant
P3277 Progesterone 3-(O-carboxymethyl)oxime
R9907 Progesterone Receptor human membrane suspension
P3492 Monoclonal Anti-phospho-Progesterone Receptor (pSer190) antibody produced in mouse ~1 mg/mL, clone 1154, purified immunoglobulin, buffered aqueous solution
P7556 Progesterone-Water Soluble powder, BioReagent, suitable for cell culture
R0500 Reichstein’s substance S ≥98%
SML1469 Ulipristal acetate ≥98% (HPLC)