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SML1189   4-P-PDOT ≥98% (HPLC) 4-P-PDOT is a slelctive MT2 melatonin receptor antagonist 300 fold selective for MT2 (MEL-1B-R) vs MT1 (MEL-1A-R) melatonin receptor subtype.
H0627 6-Hydroxymelatonin Melatonin metabolite with agonist activity.
A1362 Agomelatine ≥98% (HPLC) Agomelatine is an extremely potent agonist at both melatonin receptors (MT1 and MT2), with additional antagonism at 5HT2C. It is a novel antidepressant with many desired in vivo properties, including neuroprotection and neurogenesis in depression-sensitive brain areas. Agomelatine′s efficacy appears to be due to both melatonergic and serotonergic properties. In neurogenesis assays, both in vitro and in vivo, the compound effects were differentially affected by antagonists for MT1/MT2 and 5HT2C, demonstrating actions through all three receptors.
C5749 CGP 52608 ≥98%, solid CGP 52608 is a specific activator of retinoic acid receptor-related orphan receptor α (RORA).
I5531 IIK7 solid Melatonin receptor agonist
K1888   K 185 solid Melatonin receptor antagonist.
L2407 Luzindole ≥90% Melatonin receptor antagonist
461326 Melatonin ≥99.5%  
M5250 Melatonin powder, ≥98% (TLC) Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.
Melatonin is characterized with variety of properties such as antioxidant, autocoid, paracoid and hormonal properties, as well as anti- inflammatory and anti-apoptotic properties. Melatonin is implicated in the regulation of seasonal reproduction, energy metabolism and thermoregulation in mammals. Melatonin plays a vital role in the lessening of neonatal hypoxia–ischemia (HI) induced endoplasmic reticulum (ER) stress and conserves sirtuin 1( SIRT-1) expression.
A1824 N-Acetyl-5-hydroxytryptamine ≥99% (TLC), powder Immediate precursor of melatonin. It is formed from serotonin and acetyl-CoA in a reaction catalyzed by serotonin N-acetyl transferase, the rate-limiting enzyme in melatonin biosynthesis. This indoleamine is a weak agonist at melatonin receptors, and has moderate effects on G-protein stimulation and inhibition of cAMP accumulation.
A7342 N-Acetyltryptamine powder Mixed agonist-antagonist at melatonin receptors; antioxidant.