Immuno-Oncology Research Tools and Solutions

 


 

Immuno-Oncology Cell Lines

Whether you need screening tools for CAR/TCR therapies and mAB development, target cells for efficacy testing, or potency assays for clinical development, we provide functional biologically-relevant solutions to help you save time, accelerate your immuno-oncology research, and simplify your workflow.

Our immuno-oncology cell lines are innovative research tools for biologics discovery and clinical development. These are the perfect cell-based assay tools you need for the entire drug discovery and clinical development process.

 

 

 

Tumor-Associated Antigen Panel Cell Lines

Tumor-Associated Antigen Panel Cell Lines

The tumor-associated antigen panel cell lines are a series of up to three gene-edited cell lines that express individual tumor antigens at KO, low, and high levels. These cell-based assays contain consistent level of antigen expression with the endogenous antigen target knocked out.

 

 

Monoallelic HLA Panel Cell Lines

Monoallelic HLA Panel Cell Lines

The HLA panels are a series of up to ten gene-edited cell lines that express individual HLAs plus a negative control MHC class I HLA KO cell line in biologically-relevant parental cells. Suitable application for potency assays for CAR-T and mAb testing.

 

 

Consistency for each assay and applications

Our immuno-oncology cell lines will help you effectively produce reliable and consistent results for several assays and applications, including, but not limited to:

  • Cytokine Release Assays
  • ADCC Assays
  • Cytotoxicity Assays
  • Live Cell Imaging Potency Assays
  • T Cell Activation Assays
  • FACS Analysis
  • Cytokine Release Assays
  • Potency Assays

 

 

Products & Resources

 

Human Tumor Antigen Panels

  • Raji CD19
  • A549 EGFR
  • A375 NY-ESO-1
  • A549 EGFRvIII

 

Monoallelic HLA Panel Cell Lines (Coming Soon)
Parental Cell Lines
Raji, A549, Jurkat

HLA Subtypes
HLA-A*01:01, HLA-A*02:01, HLA-A*03:01, HLA-A*11:01, HLA-A*24:02, HLA-B*44:02, HLA-A*07:02, HLA-B*08:01, HLA-A*35:01, HLA-B*40:01