Biological Buffers


Synonym: N-(2-Hydroxyethyl)piperazine-N′-(4-butanesulfonic acid)

Homolog of HEPES and EPPS with higher pKa and similar utility in biological systems1.
Useful pH Range 7.6 - 9.0
Working concentration range 10mM3


        Comparison of products by grade or quality level
Name CAS Molecular Formula Mol Wt Reagent Grades Life Science Grades PharmaGrade  Solutions
HEPBS 161308-36-7 C10H22N2O4S 266.36






Interaction Comments

No reported interaction


Literature References

  1. Thiel T, Liczkowski L, Bissen ST. J Biochem Biophys Methods. 1998 Nov 18;37(3):117-29.
  2. Ferreira CM, Pinto IS, Soares, EV, Soares HM. 2015 Royal Society of Chemistry 30989- 31003
  3. Maki BA, Popescu GK, Extracellular Ca2+ ions reduce NMDA receptor conductance and gating, Journal of General Physiology 2014 (144;5) pp. 379-392