Functional Genomics & RNAi

TargeTron References

Title Author / Journal
Construction of an Alpha Toxin Gene Knockout Mutant of Clostridium perfringens Type A by Use of a Mobile Group II Intron (273 Kb PDF)
Chen, Y., et al.
Appl. and Env. Micro., 2005; 71: 7542-7.
Disruption of a toxin gene by introduction of a foreign gene into the chromosome of Clostridium perfringens using targetron-induced mutagenesis
Chen, Y., et al.
Plasmid, 2007; Sep; 58(2): 182-9.
Genetic Manipulation of Lactococcus lactis by Using Targeted Group II Introns: Generation of Stable Insertions without Selection (897 Kb PDF)
Frazier et al.
Appl. and Env. Micro., 2003; 69: 1121-8.
The ClosTron: A universal gene knock-out system for the genus Clostridium
Heap, J. T., et al.
J. Microbiol. Methods, 2007; Sep; 70(3): 452-64.
Group II Introns as Controllable Gene Targeting Vectors for Genetic Manipulation of Bacteria (1.52 Mb PDF)
Karberg, M., et al.
Nature Biotechnology, 2001; 19: 1162-7.
Type III Secretion System of Proteus mirabilis HI4320 Does Not Contribute to Virulence in the Mouse Model of Ascending Urinary Tract Infection
Pearson, M., et al. 2007; (In press).
Use of Computer-designed Group II Introns to Disrupt Escherichia Coli DexH/D-box Protein and DNA Helicase Genes (2.04 Mb PDF)
Perutka, J., et al.
J. Mol. Bio., 2003; 336: 421-39.
Gene Targeting in Gram-Negative Bacteria by Use of Mobile Group II Intron ("Targetron") Expressed from a Broad-Host Range Vector
Yao, J., et al.
Appl. Environ. Microbiol., 2007; Apr; 73(8): 2735-43.

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