Publications for Erenna®/SMCxPRO™

January 2020

Erenna®/SMCxPRO™ Ultra-Sensitive Immunoassay


Ultrasensitive quantitative measurement of huntingtin phosphorylation at residue S13
Biochemical and Biophysical Research Communications, Volume 521, Issue 315 January 2020, Pages 549-554
Cristina Cariulo, Margherita Verani, Paola Martufi, Raffaele Ingenito, Andrea Caricasole

December 2019

Erenna®/SMCxPRO™ Ultra-Sensitive Immunoassay


Apremilast mechanism of efficacy in systemic-naive patients with moderate plaque psoriasis: Pharmacodynamic results from the UNVEIL study
Journal of Dermatological Science, Volume 96, Issue 3, December 2019, Pages 126-133
Bruce Strober, Ali Alikhan, Benjamin Lockshin, Rebecca Shi, Peter Schafer

CellASIC® ONIX Microfluidic System


Live-cell imaging of mitochondrial motility and interactions in Drosophila neurons and yeast
Methods in Cell Biology, In press, corrected proof, Available online 12 December 2019
Pin-Chao Liao, Ryo Higuchi-Sanabria, Theresa C. Swayne, Cierra N. Sing, xLiza A. Pon

November 2019

Early quantification of systemic inflammatory-proteins predicts long-term treatment response to Tofacitinib and Etanercept: Psoriasis response predictions using blood
Journal of Investigative Dermatology, In press, journal pre-proof, Available online 6 November 2019
Lewis E. Tomalin, Jaehwan Kim, Joel Correa da Rosa, Julie Lee, Mayte Suárez-Fariñas

October 2019

Clinical determinants of plasma cardiac biomarkers in patients with stable chest pain.
Heart. 2019 Nov; Volume 105, Issue 22
Bing R1, Henderson J1, Hunter A1, Williams MC1,2, Moss AJ1, Shah ASV1, McAllister DA3, Dweck MR1,2, Newby DE1,2, Mills NL1,4, Adamson PD1,5.

September 2019

Variation in renal responses to exercise in the heat with progressive acclimatisation
Journal of Science and Medicine in Sport, Volume 22, Issue 9, September 2019, Pages 1004-1009
Jessica Omassoli, Neil E. Hill, David R. Woods, Simon K. Delves, Michael J. Stacey
Apremilast Mechanism of Efficacy in Systemic-Naive Patients With Moderate Plaque Psoriasis: Pharmacodynamic Results From the UNVEIL Study
Journal of Dermatological Science, In press, journal pre-proof, Available online 10 September 2019
Bruce Strober, Ali Alikhan, Benjamin Lockshin, Rebecca Shi, Peter Schafer

August 2019

Variation in renal responses to exercise in the heat with progressive acclimatisation
Research article
Journal of Science and Medicine in Sport, Volume 22, Issue 9, September 2019, Pages 1004-1009
Jessica Omassoli, Neil E. Hill, David R. Woods, Simon K. Delves, Michael J. Stacey

July 2019

Cardiac Myosin-Binding Protein C to Diagnose Acute Myocardial Infarction in the Pre-Hospital Setting
J Am Heart Assoc.
Kaier TE, Stengaard C, Marjot J, Sørensen JT, Alaour B, Stavropoulou-Tatla S, Terkelsen CJ, Williams L, Thygesen K, Weber E, Marber M, Bøtker HE.

June 2019

Target engagement in an alzheimer trial: Crenezumab lowers amyloid β oligomers in cerebrospinal fluid Ann Neurol. 
2019 Jun 5. doi: 10.1002/ana.25513. [Epub ahead of print]
Yang T, Dang Y, Ostaszewski B, Mengel D, Steffen V, Rabe C, Bittner T, Walsh DM, Selkoe DJ
Guselkumab efficacy after withdrawal is associated with suppression of serum IL-23-regulated IL-17 and IL-22 in psoriasis: VOYAGE 2 studyJ Invest Dermatol. 
2019 Jun 14. pii: S0022-202X(19)31755-5. doi: 10.1016/j.jid.2019.05.016. [Epub ahead of print]
Gordon KB, Armstrong AW, Foley P, Song M, Shen YK, Li S, Muñoz-Elías EJ, Branigan P, Liu X, Reich K
Secukinumab treatment does not alter the pharmacokinetics of the CYP3A4 substrate midazolam in patients with moderate to severe psoriasis Clin Pharmacol Ther. 
2019 Jun 22. doi: 10.1002/cpt.1558. [Epub ahead of print]
Bruin G, Hasselberg A, Koroleva I, Milojevic J, Calonder C, Soon R, Woessner R, Pariser DM, Boutouyrie-Dumont B
Impact of High Altitude Therapy on Type-2 Immune Responses in Asthma Patients Allergy. 
2019 Jul 3. doi: 10.1111/all.13967. [Epub ahead of print] Bo
onpiyathad T, Capova G, Duchna HW, Croxford AL, Farine H, Dreher A, Clozel M, Schreiber J, Kubena P, Lunjani N, Mirer D, Rückert B, Satitsuksanoa P, Tan G, Groenen PMA, Akdis M, Strasser DS, Renner ED, Akdis CA

May 2019

Clinical determinants of plasma cardiac biomarkers in patients with stable chest pain
Original research article
Coronary artery disease [Epub ahead of print]
Rong Bing, James Henderson, Amanda Hunter, Michelle C Williams, Alastair J Moss, Anoop S V Shah, David A McAllister, Marc R Dweck, David E Newby, Nicholas L Mills, Philip D Adamson

April 2019

Quantitation of low abundant soluble biomarkers using high sensitivity Single Molecule Counting technology
Research article
Methods, Volume 158, 1 April 2019, Pages 69-76
Joseph Hwang, Munmun Banerjee, Adam S. Venable, Zara Walden, Qiang XiaoKeywords: SMC, SMCxPRO, Femtomolarm, Sub-picogram, Bead-based assay, cTnI
Combining single molecule counting with bead-based multiplexing to quantify biological inflammation time course following skeletal muscle injury
Research Article
Methods, Volume 158, 1 April 2019, Pages 77-80
Elizabeth A. Tanner, Melody A. Gary, Asheal A. Davis, Brian K. McFarlin
Keywords: Bead-based analysis, Peripheral muscle injury, Systemic inflammation, Single Molecule Counting (SMC), Cytokines

March 2019

Quantitation of low abundant soluble biomarkers using high sensitivity Single Molecule Counting technology
Research Article
Methods, Volume 158, 1 April 2019, Pages 69-76
Joseph Hwang, Munmun Banerjee, Adam S. Venable, Zara Walden, Qiang Xiao
Keywords: SMC, SMCxPRO, Femtomolar, Sub-picogram, Bead-based assay, cTnI
Profiling Immune Expression to Consider Repurposing Therapeutics for the Ichthyoses
Review Article
Journal of Investigative Dermatology, Volume 139, Issue 3, March 2019, Pages 535-540
Amy S. Paller
Keywords: Ichthyoses, IL-17– and IL-22–expressing T cells, Psoriasis
Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease
Featured article
Alzheimer's & Dementia, In press, corrected proof, Available online 4 March 2019
Suzanne E. Schindler, Yan Li, Kaitlin W. Todd, Elizabeth M. Herries… Dominantly Inherited Alzheimer Network
Keywords: Cerebrospinal fluid, Biomarkers, Dementia, Alzheimer's disease, Autosomal-dominant Alzheimer's disease, Neuroinflammation, Erenna

February 2019

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease
Featured article
Alzheimer's & Dementia, In press, corrected proof, Available online 4 March 2019
Suzanne E. Schindler, Yan Li, Kaitlin W. Todd, Elizabeth M. Herries… Dominantly Inherited Alzheimer Network
Keywords: Cerebrospinal fluid, Biomarkers, Dementia, Alzheimer's disease, Autosomal-dominant Alzheimer's disease, Neuroinflammation, Erenna

January 2019

Droplet digital PCR of serum miR-499, miR-21 and miR-208a for the detection of functionally relevant coronary artery disease
Research Article
International Journal of Cardiology, Volume 275, 15 January 2019, Pages 129-135
M. Hortmann, J. E. Walter, L. Benning, M. Follo, C. Mueller
Keywords: Coronary artery disease; Droplet digital PCR; Micro-RNAs; Myocardial ischemia; Exercise-induced myocardial ischemia
High-sensitivity cardiac troponin T increases after stress echocardiography
Research Article
Clinical Biochemistry, Volume 63, January 2019, Pages 18-23
Eslam Samaha, Jamie Brown, Frank Brown, Sara C. Martinez, Peter Nagele
Keywords: Coronary artery disease; Myocardial ischemia; High-sensitivity cardiac troponin T; Stress echocardiography
Clinical utility of circulating interleukin-6 concentrations in the detection of functionally relevant coronary artery disease
Research Article
International Journal of Cardiology, Volume 275, 15 January 2019, Pages 20-25
Joan Walter, Yunus Tanglay, Jeanne du Fay de Lavallaz, Ivo Strebel, Christian Mueller
Keywords: Coronary artery disease; Interleukin-6; Myocardial ischemia; Exercise-induced myocardial ischemia

December 2018

TARGET ENGAGEMENT IN AN AD TRIAL: CRENEZUMAB LOWERS Aβ OLIGOMER LEVELS IN CSF
DOI: https://doi.org/10.1016/j.jalz.2018.07.012
Ting Yang, Yifan Dang, Beth Ostaszewski, David Mengel, Verena Steffen, Christina Rabe, Tobias Bittner, Dominic M. Walsh, Dennis J. Selkoe
Single Molecule Counting technology: Equivalence between a research platform and a CE-marked diagnostic platform for the quantification of cardiac troponin I
Joel Estis, Phoebe Katzenbach, Osnat Ben-Shahar, Johanna Sandlund, Luis Monsalve, Richard Livingston, Amelita Bartolome, Jeffrey Bishop
Quantitative assays to monitor huntingtin changes in preclinical and clinical hd samples
J Neurol Neurosurg Psychiatry 2018;89:A33 Kirsten Kuhlbrodt, Barbara Baldo, Wolfgang Reindl, Nikisha Carty, Karsten Tillack, Nadege Berson, Volker Mack, Chantal Bazenet, Frank Herrmann, Elizabeth vanderKam, Jonathan Bard, Ignacio Munoz-Sanjuan, Douglas Macdonald
Derivation and validation of a 0/1h-algorithm to diagnose myocardial infarction using cardiac myosin-binding protein c - direct comparison to hs-cTnI
European Heart Journal, Volume 39, Issue suppl_1, 1 August 2018, ehy565.1086 T E Kaier R Twerenbold B Alaour P Badertscher C Puelacher J Marjot J BoeddinghausT Nestelberger K Wildi D Wussler

November 2018

Decoding the synaptic dysfunction of bioactive human AD brain soluble Aβ to inspire novel therapeutic avenues for Alzheimer's disease
Acta Neuropathologica …, 2018
S Li, M Jin, L Liu, Y Dang, BL Ostaszewski, DJ Selkoe
Combining Single Molecule Counting with Bead-Based Multiplexing to Quantify Biological Inflammation Time Course Following Skeletal Muscle Injury
Methods, 2018 - Elsevier
EA Tanner, MA Gary, AA Davis, BK McFarlin
D06 Quantitative assays to monitor huntingtin changes in pre-clinical and clinical hd samples
2018 - jnnp.bmj.com
K Kuhlbrodt, B Baldo, W Reindl, N Carty, K Tillack
TARGET ENGAGEMENT IN AN AD TRIAL: CRENEZUMAB LOWERS Aβ OLIGOMER LEVELS IN CSF
Dementia: The …, 2018 - alzheimersanddementia.com
T Yang, Y Dang, B Ostaszewski

October 2018

Clinical utility of circulating interleukin-6 concentrations in the detection of functionally relevant coronary artery disease
International Journal of Cardiology
In press, corrected proof, Available online 12 October 2018
Joan Walter, Yunus Tanglay, Jeanne du Fay de Lavallaz, Ivo Strebel, Christian Mueller
APOE ε4 is associated with higher levels of CSF SNAP-25 in prodromal Alzheimer’s disease
Neuroscience Letters
Volume 685, 15 October 2018, Pages 109-113
Shanshan Wang, Jie Zhang, Tengwei Pan, for Alzheimer’s Disease Neuroimaging Initiative
Quantitation of low abundant soluble biomarkers using high sensitivity Single Molecule Counting technology
Methods
In press, corrected proof, Available online 28 October 2018
Joseph Hwang, Munmun Banerjee, Adam S. Venable, Zara Walden, Qiang Xiao

September 2018

Synergistic cytokine effects as apremilast response predictors in patients with psoriasis
Journal of Allergy and Clinical Immunology, Volume 142, Issue 3, September 2018, Pages 1010-1013.e6
Sandra Garcet, Kristine Nograles, Joel Correa da Rosa, Peter H. Schafer, James G. Krueger
AAV5-miHTT Gene Therapy Demonstrates Broad Distribution and Strong Human Mutant Huntingtin Lowering in a Huntington’s Disease Minipig Model
Molecular Therapy, Volume 26, Issue 9, 5 September 2018, Pages 2163-2177
Melvin M. Evers, Jana Miniarikova, Stefan Juhas, Astrid Vallès, …Pavlina Konstantinova

July 2018

An Integrated model of Alopecia Areata biomarkers highlights both Th1/Th2 up-regulation   
Journal of Allergy and Clinical Immunology, Available online 5 July 2018, Pages
Teresa Song, Ana B. Pavel, Huei-Chi Wen, Kunal Malik, Yeriel Estrada, Juana Gonzalez, Peter Hashim, John Nia, Danielle Baum, Grace Kimmel, Giselle K. Singer, James G. Krueger, Emma Guttman-Yassky

June 2018

Screening for Cardiac Disease with Genetic Risk Scoring, Advanced ECG, Echocardiography, Protein Biomarkers and Metabolomics   
Heart, Lung and Circulation, Volume 27, Supplement 1, 2018, Pages S8
Patrick Gladding, Clementina Dugo, Yvonne Wynne, Heather Semple, Kevin Smith, Phillip Shepherd, Erica Zarate, Peter Larsen, Silas Vilas-Boas
Synergistic Cytokine Effects as Apremilast Response Predictors in Patients With Psoriasis   
Journal of Allergy and Clinical Immunology, Available online 21 June 2018, Pages
Sandra Garcet, Kristine Nograles, Joel Correa da Rosa, Peter H. Schafer, James G. Krueger
AAV5-miHTT gene therapy demonstrates broad distribution and strong human mutant huntingtin lowering in a Huntington disease minipig model
Original Research Article
Molecular Therapy, Available online 25 June 2018, Pages
Melvin M. Evers, Jana Miniarikova, Stefan Juhas, Astrid Vallès, Bozena Bohuslavova, Jana Juhasova, Helena Kupcova Skalnikova, Petr Vodicka, Ivona Valekova, Cynthia Brouwers, Bas Blits, Jacek Lubelski, Hana Kovarova, Zdenka Ellederova, Sander J. van Deventer, Harald Petry, Jan Motlik, Pavlina Konstantinova
Standardized Immunomonitoring: Separating the Signals from the Noise
Review Article
Trends in Biotechnology, Available online 29 June 2018, Pages
Darragh Duffy

May 2018

Ichthyosis molecular fingerprinting shows profound Th17-skewing and a unique barrier genomic signature
Original Research Article
Journal of Allergy and Clinical Immunology, Available online 24 May 2018, Pages
Kunal Malik, Helen He, Thy Nhat Huynh, Gary Tran, Kelly Mueller, Kristina Doytcheva, Yael Renert-Yuval, Tali Czarnowicki, Shai Magidi, Margaret Chu, Yeriel D. Estrada, Huei-Chi Wen, Xiangyu Peng, Hui Xu, Xiuzhong Zheng, James G. Krueger, Amy S. Paller, Emma Guttman-Yassky
High-Sensitivity Cardiac Troponin I and the Diagnosis of Coronary Artery Disease in Patients With Suspected Angina Pectoris ORIGINAL ARTICLE
Circulation: Cardiovascular Quality and Outcomes. 2018;11:e004227 Originally published February 14, 2018
Philip D. Adamson, Amanda Hunter, Debbie M. Madsen, Anoop S.V. Shah, David A. McAllister, Tania A. Pawade, Michelle C. Williams, Colin Berry, Nicholas A. Boon, Marcus Flather, John Forbes, Scott McLean, Giles Roditi, Adam D. Timmis, Edwin J.R. van Beek, Marc R. Dweck, Hans Mickley, Nicholas L. Mills, David E. Newby
Association between serum interleukin‐17A and clinical response to tofacitinib and etanercept in moderate to severe psoriasis Original ArticleClinical and Experimental Dermatology. 2018 May 10
L. Fitz, W. Zhang, C. Soderstrom, S. Fraser, J. Lee, A. Quazi, R. Wolk, C. A. Mebus, H. Valdez, G. Berstein
Neurogranin as Cerebrospinal Fluid Biomarker for Alzheimer Disease: An Assay Comparison Study Research Article
Clinical Chemistry, Published May 2018
Eline A.J. Willemse, Ann De Vos, Elizabeth,M. Herries, Ulf Andreasson, Sebastiaan Engelborghs, Wiesje M. van der Flier, Philip Scheltens, Dan Crimmins, Jack H. Ladenson, Eugeen Vanmechelen, Henrik Zetterberg, Anne M. Fagan, Kaj Blennow, Maria Bjerke, Charlotte E. Teunissen
Single‐Molecule Counting of High‐Sensitivity Troponin I in Patients Referred for Diagnostic Angiography: Results From the CASABLANCA (Catheter Sampled Blood Archive in Cardiovascular Diseases) Study ORIGINAL RESEARCH
Journal of the American Heart Association. 2018;7:e007975 Originally published March 8, 2018
Cian P. McCarthy, Nasrien E. Ibrahim, Asya Lyass, Yiwei Li, Hanna K. Gaggin, Mandy L. Simon, Renata Mukai, Parul Gandhi, Noreen Kelly, Shweta R. Motiwala, Roland R. J. van Kimmenade, Joseph M. Massaro, Ralph B. D'Agostino, James L. Januzzi

April 2018

The NET-effect of combining rituximab with belimumab in severe systemic lupus erythematosus
Original Research Article
Journal of Autoimmunity, Available online 7 April 2018, Pages
Tineke Kraaij, Sylvia W.A. Kamerling, Esther N.M. de Rooij, Paul L.A. van Daele, Obbo W. Bredewold, Jaap A. Bakker, Ingeborg M. Bajema, Hans U. Scherer, Rene E.M. Toes, Tom J.W. Huizinga, Ton J. Rabelink, Cees van Kooten, Y.K. Onno Teng
Asian atopic dermatitis serum is characterized by Th2/Th22-activation, highly correlated with non-lesional skin measures.
Journal of Allergy and Clinical Immunology, Available online 11 April 2018, Pages
Huei-Chi Wen, Tali Czarnowicki, Shinji Noda, Kunal Malik, Ana B. Pavel, Saeko Nakajima, Tetsuya Honda, Jung U. Shin, Hemin Lee, Margaret Chou, Yeriel Estrada, Xiuzhong Zheng, Hui Xu, James G. Krueger, Kwang-Hoon Lee, Kenji Kabashima, Emma Guttman-Yassky
Ultrasensitive label-free optical microfiber coupler biosensor for detection of cardiac troponin I based on interference turning point effect
Biosensors and Bioelectronics Volume 106, 30 May 2018, Pages 99-104,,
doi.org/10.1016/j.bios.2018.01.061
Wenchao Zhou, Kaiwei Li, Youlian Wei, PengHao, Mingbo Chi, Yongshun Liu, Yihui Wu
CARDIAC TROPONIN I AND SUBCLINICAL CARDIOVASCULAR DISEASE
Journal of the American College of Cardiology, Volume 71, Issue 11, Supplement, 10–12 March 2018, Page A130, doi.org/10.1016/S0735-1097(18)30671-5
Esther Joo, Sirous Darabian, Yasna Nozari, Rostam Vahoumeni, Nasim Sheidaee, Niquelle Brown Wade, Matthew Budoff
Prospective Validation of a Biomarker-Based Rule Out Strategy for Functionally Relevant Coronary Artery Disease
Clin Chem. 2018 Feb;64(2):386-395. doi: 10.1373/clinchem.2017.277210. Epub 2017 Oct 16.
Walter JE, Honegger U, Puelacher C, Mueller D, Wagener M, Schaerli N, Strebel I, Twerenbold R, Boeddinghaus J, Nestelberger T, Sazgary L, Marbot S, du Fay de Lavallaz J, Kaiser C, Osswald S, Wild D, Rentsch K, Zellweger M, Reichlin T, Mueller C.
Comprehensive Age and Sex 99th Percentiles for a High-Sensitivity Cardiac Troponin I Assay
Clin Chem. 2018 Feb;64(2):398-399. doi: 10.1373/clinchem.2017.276972. Epub 2017 Oct 18.
Estis J, Wu AHB, Todd J, Bishop J, Sandlund J, Kavsak PA.

March 2018

Longitudinal decreases in multiple cerebrospinal fluid biomarkers of neuronal injury in symptomatic late onset Alzheimer's disease
Original Research Article
Alzheimer's & Dementia, Available online 23 March 2018, Pages

Courtney L. Sutphen, Lena McCue, Elizabeth M. Herries, Chengjie Xiong, Jack H. Ladenson, David M. Holtzman, Anne M. Fagan, ADNI
Prevalence, predictors and clinical outcome of residual congestion in acute decompensated heart failure
Original Research Article
International Journal of Cardiology, Volume 258, 1 May 2018, Pages 185-191

Jorge Rubio-Gracia, Biniyam G. Demissei, Jozine M. ter Maaten, John G. Cleland, Christopher M. O'Connor, Marco Metra, Piotr Ponikowski, John R. Teerlink, Gad Cotter, Beth A. Davison, Michael M. Givertz, Daniel M. Bloomfield, Howard Dittrich, Kevin Damman, Juan I. Pérez-Calvo, Adriaan A. Voors
Prospective Validation of a Biomarker-Based Rule Out Strategy for Functionally Relevant Coronary Artery Disease.
Walter JE, Honegger U, Puelacher C, Mueller D, Wagener M, Schaerli N, Strebel I, Twerenbold R, Boeddinghaus J,
Nestelberger T, Sazgary L, Marbot S, du Fay de Lavallaz J, Kaiser C, Osswald S, Wild D, Rentsch K, Zellweger M, Reichlin T, Mueller C.
Clin Chem. 2018 Feb;64(2):386-395. doi: 10.1373/clinchem.2017.277210. Epub 2017 Oct 16.
Quantifying the Release of Biomarkers of Myocardial Necrosis from Cardiac Myocytes and Intact Myocardium.
Marjot J, Kaier TE, Martin ED, Reji SS, Copeland O, Iqbal M, Goodson B, Hamren S, Harding SE, Marber MS.
Clin Chem. 2017 May;63(5):990-996. doi: 10.1373/clinchem.2016.264648. Epub 2017 Apr 4.
Evaluation of highly sensitive immunoassay technologies for quantitative measurements of sub-pg/mL levels of cytokines in human serum.
Yeung D, Ciotti S, Purushothama S, Gharakhani E, Kuesters G, Schlain B, Shen C, Donaldson D, Mikulskis A.
J Immunol Methods. 2016 Oct;437:53-63. doi: 10.1016/j.jim.2016.08.003. Epub 2016 Aug 21.
Can a Point-of-Care Troponin I Assay be as Good as a Central Laboratory Assay? A MIDAS Investigation.
Peacock WF, Diercks D, Birkhahn R, Singer AJ, Hollander JE, Nowak R, Safdar B, Miller CD, Peberdy M, Counselman F, Chandra A, Kosowsky J, Neuenschwander J, Schrock J, Lee-Lewandrowski E, Arnold W, Nagurney J.
Ann Lab Med. 2016 Sep;36(5):405-12. doi: 10.3343/alm.2016.36.5.405.
The development and application of a high-sensitivity immunoassay for cardiac myosin-binding protein C.
Marjot J, Liebetrau C, Goodson RJ, Kaier T, Weber E, Heseltine P, Marber MS.
Transl Res. 2016 Apr;170:17-25.e5. doi: 10.1016/j.trsl.2015.11.008. Epub 2015 Dec 8.
Longitudinal studies of cardiac troponin I concentrations in serum from male cynomolgus monkeys: resting values and effects of oral and intravenous dosing on biologic variability.
Schultze AE, Anderson JM, Kern TG, Justus RW, Lee HY, Zieske LR, Goodson RJ, Florey SH.
Vet Clin Pathol. 2015 Sep;44(3):465-71. doi: 10.1111/vcp.12272. Epub 2015 Jul 14.
A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid.
Yang T, O'Malley TT, Kanmert D, Jerecic J, Zieske LR, Zetterberg H, Hyman BT, Walsh DM, Selkoe DJ.
Alzheimers Res Ther. 2015 Mar 22;7(1):14. doi: 10.1186/s13195-015-0100-y. eCollection 2015.
Prognostic performance of a high-sensitivity assay for cardiac troponin I after non-ST elevation acute coronary syndrome: Analysis from MERLIN-TIMI 36.
Bonaca MP, O'Malley RG, Murphy SA, Jarolim P, Conrad MJ, Braunwald E, Sabatine MS, Morrow DA.
Eur Heart J Acute Cardiovasc Care. 2015 Oct;4(5):431-40. doi: 10.1177/2048872614564081. Epub 2014 Dec 23.
The utility of serum biomarkers to detect myocardial alterations induced by Imatinib in rats.
Herman E, Knapton A, Zhang J, Estis J, Todd J, Lipshultz S.
Pharmacol Res Perspect. 2014 Feb;2(1):e00015. doi: 10.1002/prp2.15. Epub 2014 Mar 3.
Due diligence in the characterization of matrix effects in a total IL-13 Singulex™ method.
Fraser S, Soderstrom C.
Bioanalysis. 2014 Apr;6(8):1123-9. doi: 10.4155/bio.14.42.
Assay formats: Recommendation for best practices and harmonization from the global bioanalysis consortium harmonization team.
Dudal S, Baltrukonis D, Crisino R, Goyal MJ, Joyce A, Osterlund K, Smeraglia J, Taniguchi Y, Yang J.
AAPS J. 2014 Mar;16(2):194-205. doi: 10.1208/s12248-013-9552-9. Epub 2013 Dec 17. Review.
Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays.
Todd J, Simpson P, Estis J, Torres V, Wub AH.
Cytokine. 2013 Dec;64(3):660-5. doi: 10.1016/j.cyto.2013.09.018. Epub 2013 Oct 12.
Interleukin 17F level and interferon β response in patients with multiple sclerosis.
Hartung HP, Steinman L, Goodin DS, Comi G, Cook S, Filippi M, O'Connor P, Jeffery DR, Kappos L, Axtell R, Knappertz V, Bogumil T, Schwenke S, Croze E, Sandbrink R, Pohl C.
JAMA Neurol. 2013 Aug;70(8):1017-21. doi: 10.1001/jamaneurol.2013.192.
Quantitative determination of human interleukin 22 (IL-22) in serum using Singulex-Erenna® technology.
Shukla R, Santoro J, Bender FC, Laterza OF.
J Immunol Methods. 2013 Apr 30;390(1-2):30-4. doi: 10.1016/j.jim.2013.01.002. Epub 2013 Jan 10.
Baseline serum cardiac troponin I concentrations in Sprague-Dawley, spontaneous hypertensive, Wistar, Wistar-Kyoto, and Fisher rats as determined with an ultrasensitive immunoassay.
Herman E, Knapton A, Rosen E, Zhang J, Estis J, Agee SJ, Lu QA, Todd JA, Lipshultz SE.
Toxicol Pathol. 2011 Jun;39(4):653-63. doi: 10.1177/0192623311406931. Epub 2011 May 10.
Defining the serum 99th percentile in a normal reference population measured by a high-sensitivity cardiac troponin I assay.
Apple FS, Simpson PA, Murakami MM.
Clin Biochem. 2010 Aug;43(12):1034-6. doi: 10.1016/j.clinbiochem.2010.05.014. Epub 2010 May 27.
Assessment of the toxicity of hydralazine in the rat using an ultrasensitive flow-based cardiac troponin I immunoassay.
Mikaelian I, Coluccio D, Hirkaler GM, Downing JC, Rasmussen E, Todd J, Estis J, Lu QA, Nicklaus R.
Toxicol Pathol. 2009 Dec;37(7):878-81. doi: 10.1177/0192623309351894.
Analytical validation of a highly sensitive microparticle-based immunoassay for the quantitation of IL-13 in human serum using the Erenna immunoassay system.
St Ledger K, Agee SJ, Kasaian MT, Forlow SB, Durn BL, Minyard J, Lu QA, Todd J, Vesterqvist O, Burczynski ME.
J Immunol Methods. 2009 Oct 31;350(1-2):161-70. doi: 10.1016/j.jim.2009.08.012. Epub 2009 Sep 2.
Ultrasensitive cross-species measurement of cardiac troponin-I using the Erenna immunoassay system.
Schultze AE, Konrad RJ, Credille KM, Lu QA, Todd J.
Toxicol Pathol. 2008 Oct;36(6):777-82. doi: 10.1177/0192623308322016. Epub 2008 Jul 22
Ultrasensitive flow-based immunoassays using single-molecule counting.
Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P.
Clin Chem. 2007 Nov;53(11):1990-5. Epub 2007 Sep 21.