On-Demand Webinar: 3D Cell Culture Models for Respiratory Diseases and COVID-19 Research
 

What Does it Cover?

The current COVID-19 viral pandemic has galvanized the research community in a search for effective vaccines and a better understanding of the SARS-COV-2 virus. Relevant cell models are needed to aid high-throughput screening of anti-viral agents along with higher order tissue models to better understand the biology of viral infection. In this webinar, we will discuss two lung models for respiratory research: 16HBE14o-, an immortalized human bronchial epithelial cell line that retains characteristic features of normal differentiated bronchial epithelial cells and a human lung organoid culture system with highly complex structures that resemble the in vivo conducting airways (branching structure) and early gas-exchange units (alveolar structure).  

Both the 16HBE14o- human bronchial epithelial cell line and the lung bud organoids (LBOs) express ACE2, the receptor for the novel SARS-CoV-2 virus that causes COVID-19 and TMPRSS2, the serine protease that enhances SARS-CoV-2 viral entry. This presentation will discuss some of the unique features, advantages and applications of the 16HBE14o- human bronchial epithelial cells and the human lung organoid culture system for respiratory research.
 

What Will You Learn?

Unique features, advantages, and application of 16HBE14o- human bronchial epithelial cells and the human lung organoid culture system.

 

Speaker Bio
Min Lu, Ph.D.
Senior Scientist in Cellular Assays, Biological Reagents & Kits, { Merck }
Min Lu received her Ph.D. degree from Dept. of Immunology, Kyoto University and had her post-doctoral training at the BC Cancer Research Center, Vancouver. She joined Millipore in 2009 and has worked on various projects in R&D Stem Cell/Cellular Assay. Her current research interest focuses on medium development and human iPSCs or patient tissue-derived organoids.