Metabolomics

Glycolysis or Glycolytic Pathway

Aerobic and Anerobic Glycolysis

Glycolysis is the almost universal pathway that converts glucose into pyruvate together with nicotinamide adenine dinucleotide (NADH) and a little adenosine triphosphate (ATP).

In aerobic glycolysis, which occurs in aerobic organisms, the pyruvate passes into the mitochondria where it is completely oxidised by O2 into CO2 and H2O and its potential energy largely conserved as ATP. Pyruvate generated via aerobic glycolysis would then go into the TCA or Krebs cycle. In the absence of sufficient oxygen, the pyruvate is reduced by the NADH via anaerobic glycolysis or fermentation to a wide range of products, especially lactate in animals and ethanol in yeasts.

Phosphorylation in Aerobic RespirationTCA or Krebs Cycle | Aerobic Glycolysis and the Warburg Effect

Enzyme Explorer | Glycolysis Enzymes & Metabolites

View Glycolysis Animation