Histone Lysine Demethylase Inhibitors

Lysine specific demethylase I (LSDI, KIA0601, BHC10) has close homology to monoamine oxidases (MAOs), and hence the classic MAO inhibitors pargyline and tranylcypromine have been found to inhibit LSD1, although not with high potency (>100μM).

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P8013 Pargyline hydrochloride Pargyline hydrochloride acts as a histone demethylase inhibitor. It has antihypertensive action.
Selective MAO-B inhibitor.
human ... MAOB(4129)
P8511 trans-2-Phenylcyclopropylamine hydrochloride Non-selective MAO-A/B inhibitor.
human ... MAOA(4128), MAOB(4129)