Homobifunctional Crosslinking Reagents

Homobifunctional reagents consist of identical reactive groups on either end of a spacer arm. They are used for single step conjugation and are extremely useful when evaluating protein interactions.
There are different types of homobifunctional reagents. Homobifunctional imidoesters are useful in determining the distances between linked residues on surfaces protein that are close to each other and reversible homobifunctional crosslinkers, such as N-hydroxysuccinimide (NHS) esters, are used for identification of unknown interacting proteins.

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D8388 Dimethyl pimelimidate dihydrochloride powder
D3669 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) powder
S5799 Suberic acid bis(3-sulfo-N-hydroxysuccinimide ester) sodium salt ≥95% (H-NMR), powder