Ubiquitination Analysis

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114802 AdaAhx₃L₃VS - CAS 389064-25-9 - Calbiochem A potent, covalent, cell-permeable, irreversible inhibitor of chymotrypsin-like (50-100 nM), trypsin-like (1-5 µM), and PGPH (0.5-1 µM) activities of the 20S proteasome.
172103 Anaphase-Promoting Complex Inhibitor Negative Control, AAME - CAS 1784-05-0 - Calbiochem The Anaphase-Promoting Complex Inhibitor Negative Control, AAME, also referenced under CAS 1784-05-0, controls the biological activity of Anaphase-Promoting Complex.
208719 ALLN - CAS 110044-82-1 - Calbiochem ALLN, CAS 110044-82-1, is a cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM)., Cell-permeable inhibitor of calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM).
219465 Celastrol, Celastrus scandens - CAS 34157-83-0 - Calbiochem A cell-permeable dienone-phenolic triterpene compound that exhibits antioxidant and anti-inflammatory properties.
324800 Epoxomicin, Synthetic - Calbiochem Epoxomicin, Synthetic, CAS 134381-21-8, is a potent, specific, and irreversible inhibitor of chymotrypsin-like, trypsin-like, and peptidyl-glutamyl peptide hydrolyzing activities of the proteasome.
324801 InSolution™ Epoxomicin, Synthetic - Calbiochem InSolution™ Epoxomicin, Synthetic, is a 1 mM solution of Epoxomicin, Synthetic (Cat. No. 324800) in DMSO.
345887 Ginkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem Ginkgolic Acid (15:1), CAS 22910-60-7, is a cell-permeable analog of anacardic acid that inhibits protein SUMOylation (IC50 = 3.0 µM using RanGAP1-C2 as substrate) in an ATP-dependent manner., A cell-permeable anacardic acid analog that inhibits protein SUMO .
373225 Hdm2 E3 Ligase Inhibitor - CAS 414905-09-2 - Calbiochem The Hdm2 E3 Ligase Inhibitor, also referenced under CAS 414905-09-2, controls the biological activity of Hdm2 E3 Ligase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
373226 Hdm2 E3 Ligase Inhibitor II, HLI373 - CAS 502137-98-6 - Calbiochem The Hdm2 E3 Ligase Inhibitor II, HLI373, also referenced under CAS 502137-98-6, controls the biological activity of Hdm2 E3 Ligase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
373227 MDM2 Inhibitor VII, MEL23 - Calbiochem The MDM2 Inhibitor VII controls the biological activity of MDM2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
426100 Lactacystin, Synthetic - CAS 1258004-00-0 - Calbiochem Lactacystin, Synthetic, CAS 1258004-00-0, is an irreversible inhibitor of 20S proteasome inhibitor (IC₅₀ = 500 nM). A covalent inhibitor of the chymotrypsin & trypsin-like activities of proteasome.
426102 clasto-Lactacystin β-Lactone - CAS 154226-60-5 - Calbiochem clasto-Lactacystin β-Lactone, CAS 154226-60-5, is a cell-permeable, highly specific, irreversible 20S proteasome inhibitor., A highly specific, cell-permeable, and irreversible 20S proteasome inhibitor.
474780 MG-115 - CAS 133407-86-0 - Calbiochem Potent reversible proteasome inhibitor (Ki = 21 nM and 35 nM for 20S and 26S proteasome, respectively).
474787 MG-132, ≥95% by HPLC - CAS 133407-82-6 - Calbiochem MG-132, ≥95% by HPLC, CAS 133407-82-6, is a potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM)., Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM).
474788 InSolution™ MG-132 in EtOH, ≥95% by HPLC - Calbiochem Potent, reversible, and cell-permeable proteasome inhibitor. Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex.
474790 MG-132 - CAS 133407-82-6 - Calbiochem A cell-permeable, potent, reversible proteasome inhibitor (Ki = 4 nM).
474791 InSolution™ MG-132 - CAS 133407-82-6 - Calbiochem InSolution™ MG-132, CAS 133407-82-6, is provided as a 10 mM solution in DMSO. Acts as a potent, reversible proteasome inhibitor (Ki = 4 nM).
475858-M Met30 Antagonist, SMER3 - Calbiochem The Met30 Antagonist, SMER3 controls the biological activity of Met30. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
5.00502 Proteasome Inhibitor XXI, Z-LLLL-SF - Calbiochem
5.00517 SKP2 E3 Ligase Inhibitor II, SMIP004 - CAS 143360-00-3 - Calbiochem
5.00519 SKP2 E3 Ligase Inhibitor I, C1 - CAS 432001-69-9 - Calbiochem
5.04314 Bortezomib - CAS 179324-69-7 - Calbiochem Bortezomib, CAS 179324-69-7, is a cell-permeable, selective, slowly reversible inhibitor of 20S proteasome β5 ChTL/chymotrypsin- over β1 CL/caspase- and β2 TL/trypsin-like activity.
5.05156 SUMOylation Inhibitor III, 2-D08 - Calbiochem A cell-permeable compound that prevents the transfer of SUMO from the E2 thioester to the substrate without affecting SUMO-activating enzyme E1 (SAE-1/2) or E2 Ubc9-SUMO thioester formation.
5.05477 NAE Inhibitor, MLN4924 - CAS 951950-33-7 - Calbiochem NAE Inhibitor, MLN4924, CAS 951950-33-7, is an AMP mimetic that forms a NAE-catalyzed NEDD8 adduct, which acts as a tight-binding, ATP-competitive NAE inhibitor (IC50 = 4.7 nM).
5.06047 3,3ʹ-Diamino-4ʹ-methoxyflavone, DD1 - Calbiochem
506190 p97 ATPase Activity Inhibitor, DBeQ - Calbiochem The p97 ATPase Activity Inhibitor, DBeQ controls the biological activity of p97 ATPase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
5.06305 SKP2 E3 Ligase Inhibitor III - Calbiochem
5.08197 InSolution™ Ginkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem A 25 mM (2 mg/231 µl) sterile-filtered solution of Ginkgolic Acid (15:1) in DMSO.
5.09704 Cdc34 Inhibitor, CC0651 - CAS 1319207-44-7 - Calbiochem A cell-permeable, selective allosteric inhibitor of E2 ubiquitin-conjugating enzyme Cdc34 (IC₅₀ = 2.5 µM in a Sic1-SCFCdc4 assay).
5.09705 L-Serine-O-phosphate - CAS 407-41-0 - Calbiochem A potent agonist for group III mGlu receptor subtype 4, 6, and 8.
5.30236 SKP2 E3 Ligase Inhibitor IV - Calbiochem A cell-permeable inhibitor of SKP2-dependent p27Kip1 ubiquitination. Selectively induces the accumulation SCFSKP2 substrates in multiple myeloma RPMI 8226 cells.
5.30587 Proteasome Inhibitor XXIII, PI-1840 - Calbiochem A cell-permeable, highly potent, selective, and non-covalent inhibitor of chymotrypsin-like (CT-L) activity of 20S proteasome (IC₅₀ = 27 nM).
5.31088 VCP Inhibitor III, NMS-873 - CAS 1418013-75-8 - Calbiochem A cell-permeable, non-ATP competitive, allosteric inhibitor of VCP ATPase (IC₅₀ = 20 nM with 1 mM ATP)
5.31131 USP1-UAF1 Inhibitor, ML323 - Calbiochem A cell-permeable, selective, potent, and reversible inhibitor of USP1-UAF1 deubiquitinase (IC₅₀ = 76 nM in Ub-Rhodamine based assays). Does not disrupt USP1-UAF1 association.
5.38184 Synoviolin Inhibitor, LS-102 - Calbiochem
539160 Proteasome Inhibitor I - Calbiochem The Proteasome Inhibitor I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
539162 Proteasome Inhibitor II - Calbiochem The Proteasome Inhibitor II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
539163-M Proteasome Inhibitor III - Calbiochem Proteasome Inhibitor III, CAS 179324-22-2, is a reversible proteasome inhibitor that is structurally similar to MG-132, but displays much higher potency (Ki = 30 pM vs. 4 nM for MG-132)., The Proteasome Inhibitor III controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
539164 Proteasome Inhibitor Set I - Calbiochem Proteasome Inhibitor Set I contains 1 mg of Proteasome Inhibitor I (Cat. No. 539160), 200 µg of Lactacystin (Cat. No. 426100), and 1 mg of MG-132 (Cat. No. 474790). Supplied with a data sheet., The Proteasome Inhibitor Set I controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
539165 Proteasome Inhibitor Set II - Calbiochem The Proteasome Inhibitor Set II controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
539175 Proteasome Inhibitor IV - Calbiochem The Proteasome Inhibitor IV controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
539183 Proteasome Inhibitor VIII, β-Lactam 3 - CAS 870528-53-3 - Calbiochem
539185 Proteasome Inhibitor XX, GL5 - CAS 146304-91-8 - Calbiochem The Proteasome Inhibitor XX, GL5, also referenced under CAS 146304-91-8, controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
539187 Proteasome Inhibitor X, PI-083 - CAS 6298-15-3 - Calbiochem The Proteasome Inhibitor X, PI-083, also referenced under CAS 6298-15-3, controls the biological activity of Proteasome. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
557550 Ro106-9920 A cell-permeable tetrazolopyridazine-phenylsulfoxide compound that displays anti-inflammatory properties.
662056 Ubiquitin Aldehyde - Calbiochem Potent and specific inhibitor of multiple ubiquitin hydrolases involved in pathways of intracellular protein modification and turnover.
662086 UCH-L1 Inhibitor - CAS 668467-91-2 - Calbiochem The UCH-L1 Inhibitor, also referenced under CAS 668467-91-2, controls the biological activity of UCH-L1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
662089-M UCH-L3 Inhibitor - CAS 30675-13-9 - Calbiochem
662105 Ubiquitin E1 Inhibitor, PYR-41 - Calbiochem Ubiquitin E1 Inhibitor, PYR-41, CAS 418805-02-4, is a cell-permeable, irreversible inhibitor of ubiquitin-activating enzyme E1 activity (IC50 less than 10 µM in cell-free E1 ubiquitination reactions)., The Ubiquitin E1 Inhibitor, PYR-41 controls the biological activity of Ubiquitin E1. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
662107 UbcH13 Inhibitor, NSC697923 - CAS 343351-67-8 - Calbiochem The UbcH13 Inhibitor, NSC697923 controls the biological activity of UbcH13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
662125 Ubiquitin Isopeptidase Inhibitor I, G5 - CAS 108477-18-5 - Calbiochem The Ubiquitin Isopeptidase Inhibitor I, G5, also referenced under CAS 108477-18-5, controls the biological activity of Ubiquitin Isopeptidase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
662140 DUB Inhibitor IV, b-AP15 - CAS 1009817-63-4 - Calbiochem The DUB Inhibitor IV, b-AP15 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
662141 DUB Inhibitor V, PR-619 - Calbiochem DUB Inhibitor V, PR-619, CAS 21645-32-1, is a cell-permeable, broad-spectrum DUB inhibitor whose (C50 = 5-20 M)., The DUB Inhibitor V, PR-619 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
662142 DUB Inhibitor VI, P22077 - Calbiochem The DUB Inhibitor VI, P22077 controls the biological activity of DUB. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
662210 USP14 Inhibitor, IU1 - Calbiochem The USP14 Inhibitor, IU1 controls the biological activity of USP14. This small molecule/inhibitor is primarily used for Cell Structure applications.
681685 WP1130 - Calbiochem A cell-permeable tyrphostin compound that acts as a partially selective deubiquitinase (DUB) inhibitor and suppresses JAK-Stat signaling pathway.
S0439 SUMO-1 human ≥95% (SDS-PAGE), recombinant, expressed in E. coli (GST-tagged)
U9257 UbcH9 Conjugating Enzyme human ≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution
U6253 Ubiquitin from bovine erythrocytes BioUltra, ≥98% (SDS-PAGE), essentially salt-free, lyophilized powder
U5382 Ubiquitin human ≥95% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal FLAG® tagged), essentially salt-free, lyophilized powder
U5507 Ubiquitin human recombinant, expressed in E. coli (N-terminal histidine tagged)
U5379 Anti-Ubiquitin antibody produced in rabbit whole antiserum, lyophilized powder
U5632 Ubiquitin−Agarose saline suspension
U2258 Ubiquitin-7-amido-4-methylcoumarin solution (supplied in DMSO)
U9382 Ubiquitin-Carrier Protein H10 human ≥95% (SDS-PAGE), recombinant, expressed in E. coli (histidine-tagged), buffered aqueous glycerol solution
U2508 Ubiquitin Carrier Protein H2 human
U2383 Ubiquitin Carrier Protein H3/CDC34 human ≥95% (SDS-PAGE), recombinant, expressed in E. coli overproducing strain
U8632 Ubiquitin-Carrier Protein H5a, GST-tagged human ≥95% (SDS-PAGE), liquid
U8757 Ubiquitin-Carrier Protein H5b human ≥95% (SDS-PAGE), solution
U8882 Ubiquitin-Carrier Protein H5c human ≥95% (SDS-PAGE), recombinant, expressed in E. coli (GST-tagged), solution
U9132 Ubiquitin-Carrier Protein H7 human ≥95% (SDS-PAGE), recombinant, expressed in E. coli, liquid
U8507 Ubiquitin K48R human ≥95% (SDS-PAGE), recombinant, expressed in E. coli, solid
U2133 Ubiquitin C-terminal Hydrolase-L3