Cell Lysis and Protein Extraction

Efficient cell lysis and maximum protein extraction yields are vital to high-quality recombinant protein purification. CelLytic formulations for bacterial, mammalian, yeast or plant cell lysis result in higher protein yields than traditional physical disruption methods, such as sonication or the French press. The proprietary non-denaturing formulations are compatible with most affinity purification techniques and preserve protein function allowing for downstream analysis. CelLytic products are offered in a variety of convenient formats ranging from concentrates to tablets. Sigma-Aldrich also offers a wide range of protease inhibitor cocktails to further ensure that proteolytic degradation does not occur during cell lysis and protein extraction. Select the CelLytic formulation specific for your research needs.