X-tremeGENE™ Transfection Reagents

 Efficient Delivery of DNA, siRNA, miRNA, and CRISPR/Cas9 Components​

With a joint commitment to enable your next discovery, we exclusively offer the complete portfolio of Roche X-tremeGENE™ transfection reagents. Whether you are working with common or difficult-to-transfect cell lines, X-tremeGENE™ transfection reagents are efficient at delivering a broad range of biological materials with low cytotoxicity. Explore the resources provided below to easily identify which X-tremeGENE™ transfection reagent is suitable for your specific cell line and application needs.


Selection Tools
Browse our X-tremeGENE™ Transfection Database to easily find the best reagent for your specific applications, cell types, references and published protocols.

Explore additional transfection reagents that best fit your needs.



Transfection Resources
View our introduction to transfection and additional molecular and cell biology resources to help you with your experiment:​

X-tremeGENE™ General

Molecular Biology Handbook
Cell Culture Manual


Customer Testimonial
For Alan Alfano, a cancer researcher
at the University of Maryland,
X-tremeGENE™ HP is the transfection
reagent of choice.
Watch this video to hear his story


X-tremeGENE is a trademark of Roche. For life science research only. Not for use in diagnostic procedures.