Self-Assembly Materials

Molecular self-assembly1 is the assembly of molecules without guidance or management from an outside source. Self-assembly can occur spontaneously in nature. One such example is the self-assembly of the lipid bilayer membrane in cells.

An efficent approach to molecular self-assembly having received ample attention during the last decade is the creation of self-assembled monolayers (SAMs) using relatively weak intermolecular interactions between certain types of organic molecules, such as thiols or phosphonic acids, and a gold or oxidic surface.

SAMs have a wide range of applications including surface wetting, non-fouling property, electrochemistry, surface passivation, protein binding, DNA assembly, corrosion resistance, biological arrays and cell interactions.2-4 SAMs also are contained, in large numbers, in materials for the semiconductor electronics industry such as nanowires, nanotransistors and nanosensors.

Self-Assembly Resources:

Technical Notes and Procedures:
Preparing Self-Assembled Monolayers
Thioacetate Deprotection Procedure
Chemistry at Surfaces with SAMs and SAMDI-ToF Mass Spectrometry

Basics of Molecular Self-Assembly
From Molecules to Monolayers: Self-Assembly and Analysis, Molecule by Molecule

Material Matters
Material Matters Vol. 4 No. 3- Organic and Molecular Electronics
Material Matters Vol. 3 No. 2- Nanoscale Surface Modifications
Material Matters Vol. 1 No. 2- Molecular Self-Assembly

Material Matters Vol. 1 No. 2 (2006). 2) J.C. Love et al. Chem. Rev., 105, 1103 (2005). 3) N.K. Chaki et al. Biosensors & Bioelectronics, 17, 1 (2002). 4) A. Ulman, Chem. Rev., 96, 1533 (1996).