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803464

BS(PEG)9

Synonym(s):

1,31-Bis(2,5-dioxo-1-pyrrolidinyl) 4,7,10,13,16,19,22,25,28-nonaoxahentriacontanedioate

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Size/SKUAvailabilityPrice
100 mg
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€ 565,00

About This Item

Empirical Formula (Hill Notation):
C30H48N2O17
CAS Number:
Molecular Weight:
708.71
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22
Form:
oil

€ 565,00


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form

oil

Quality Segment

mol wt

708.71

reaction suitability

reagent type: cross-linking reagent

storage condition

desiccated

solubility

water: soluble

shipped in

ambient

storage temp.

−20°C

SMILES string

N2(C(=O)CCC2=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

InChI

1S/C30H48N2O17/c33-25-1-2-26(34)31(25)48-29(37)5-7-39-9-11-41-13-15-43-17-19-45-21-23-47-24-22-46-20-18-44-16-14-42-12-10-40-8-6-30(38)49-32-27(35)3-4-28(32)36/h1-24H2

InChI key

CQWLSZJYTZVHMU-UHFFFAOYSA-N

General description

By contrast to typical PEG reagents that contain heterogeneous mixtures of different PEG chain lengths, this PEG reagent is a homogeneous compound of defined molecular weight and spacer arm length, providing greater precision in optimization and characterization of crosslinking applications.

Application

BS(PEG)9 can be used as a cross-linker


  • To study the domain structure of BfmR, a regulator of biofilm formation in Acinetobacter baumannii.
  • In the study of the mechanism of visual excitation.

Features and Benefits

  • Reactive groups: sulfo-NHS ester (both ends)
  • Reactive towards: amino groups (primary amines)
  • NHS esters react with—NH2 groups at pH 7-9, forming stable amide bonds
  • Water-soluble; compare to non-pegylated BS3 (also soluble) and DSS (water-insoluble)
  • Membrane-impermeable, allowing for cell surface labeling
  • Irreversibly crosslink proteins or peptides by flexible PEG spacer arms
  • Polyethylene glycol spacer arms help maintain conjugate solubility
  • Pure compound with defined structure and molecular weight, ensuring reproducible protein-modification effects
  • PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity
  • Ideal for small molecule or peptide conjugations

Disclaimer

This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.

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This Item
803537803316QBD10260
solubility

water: soluble

solubility

water: soluble

solubility

soluble (>95 mg/ml in water)

solubility

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

-

reaction suitability

reagent type: cross-linking reagent

reaction suitability

reagent type: cross-linking reagent

reaction suitability

reagent type: cross-linking reagent

reaction suitability

reagent type: chemical modification reagent, reagent type: cross-linking reagent
reactivity: amine reactive

form

oil

form

liquid

form

powder

form

solid or viscous liquid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

shipped in

ambient

shipped in

ambient

shipped in

ambient

shipped in

ambient


Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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