902241
N-Hydroxysuccinimide poly(ethylene glycol)-block-poly(lactide-co-glycolide)
PEG average Mn 5000, PLGA average Mn 15000, lactide:glycolide 50:50
Synonym(s):
NHS-PEG-b-PLGA, NHS-PEG-PLGA
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About This Item
Linear Formula:
C10H14O5NS(C2H4O)nC2H4O[(C2H2O2)x(C3H4O2)y]mH
NACRES:
NA.23
UNSPSC Code:
12352111
eCl@ss:
32150917
form
powder
feed ratio
lactide:glycolide 50:50, lactide:glycolide 50:50±5
mol wt
PEG Mn 4000-6000 g/mol (by NMR), PEG average Mn 5000, PLGA Mn 13500-16500 g/mol (by NMR), PLGA average Mn 15000
color
white
suitability
conforms to structure for NMR
storage temp.
−20°C
Application
N-Hydroxysuccinimide poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a N-hydroxysuccinimide (NHS)-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the NHS-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents.
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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