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P6148

Paraformaldehyde

reagent grade, crystalline

Synonym(s):

Polyoxymethylene

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Size/SKUAvailabilityPrice
500 g

Available to ship TODAYfromCarlos Spegazzini

$161.00
1 kg

Available to ship TODAYfromCarlos Spegazzini

$291.00
5 kg

Estimated to ship onJuly 30, 2026fromCarlos Spegazzini

$803.00

About This Item

Linear Formula:
HO(CH2O)nH
CAS Number:
Molecular Weight:
30.03 (as monomer)
UNSPSC Code:
12352114
PubChem Substance ID:
NACRES:
NA.25
MDL number:
Grade:
reagent grade
Vapor pressure:
<1.45 mmHg ( 25 °C)

$161.00

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grade

reagent grade

Quality Segment

vapor density

1.03 (vs air)

vapor pressure

<1.45 mmHg ( 25 °C)

form

crystalline

autoignition temp.

572 °F

expl. lim.

73 %

dilution

(for analytical testing)

mp

120-170 °C (lit.)

density

0.88 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

[O-]#[C+H2]

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

General description

Paraformaldehyde is a cross-linking fixative. It is changed to formaldehyde by heating and by adding small amount of sodium hydroxide.

Application

Paraformaldehyde is recommended for use in the preparation of formalin fixatives for tissues or cells when the samples are to be used in florescence studies.
Paraformaldehyde has been used for fixing of cells and tissue sections during staining procedures.[1]

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Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

grade

reagent grade

grade

-

grade

-

grade

-

form

crystalline

form

powder

form

prilled

form

powder

density

0.88 g/mL at 25 °C (lit.)

density

0.88 g/mL at 25 °C (lit.)

density

0.88 g/mL at 25 °C (lit.)

density

0.88 g/mL at 25 °C (lit.)

vapor pressure

<1.45 mmHg ( 25 °C)

vapor pressure

<1.45 mmHg ( 25 °C)

vapor pressure

<1.45 mmHg ( 25 °C)

vapor pressure

<1.45 mmHg ( 25 °C)

autoignition temp.

572 °F

autoignition temp.

572 °F

autoignition temp.

572 °F

autoignition temp.

572 °F


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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Sol. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges



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Questions

1–8 of 8 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the shelf life of Product P6148, Paraformaldehyde?

    1 answer
    1. The shelf life has not been assigned but guarantee of quality is 1 year from the time of receipt for unopened bottles stored at 2-8 °C.  We expect the product to be of good quality for at least 2 years.

      Helpful?

  4. How to prepare solutions of Product P6148, Paraformaldehyde?

    1 answer
    1. Paraformaldehyde does not dissolve but rather can be depolymerized in solution. Depolymerized solutions can be prepared in water with heating to 55-60°C. If necessary, further addition of 1-2 drops of a sodium hydroxide solution may be required. Some protocols suggest that paraformaldehyde should be prepared in buffered solutions such as phosphate buffer or PBS at approximately pH 7.

      Helpful?

  5. How stable are Product P6148, Paraformaldehyde, solutions?

    1 answer
    1. Buffered solutions of 2-4% can be stored protected from light for 2-3 weeks at 2-8°C.

      Helpful?

  6. What is the difference between formaldehyde and paraformaldehyde?

    1 answer
    1. Paraformaldehyde is the polymeric form of formaldehyde. It is a solid. Formaldehyde is a gas which when dissolved in water gives a formaldehyde solution. Commercially available formaldehyde solutions usually contain 10-15% methanol, which prevents the formaldehyde from forming the polymeric paraformaldehyde.

      Helpful?

  7. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  8. What is the difference between formaldehyde and paraformaldehyde?

    1 answer
    1. Paraformaldehyde is the polymeric form of formaldehyde. Paraformaldehyde is a solid, and formaldehyde is a gas. Formaldehyde solutions consist of formaldehyde gas dissolved in a solvent of some kind.

      Helpful?

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