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04273

Sodium phosphate dibasic dodecahydrate

meets analytical specification of Ph. Eur., BP, E339, 98.5-102.5% (T)

Synonym(s):

sec-Sodium phosphate, Disodium hydrogen phosphate dodecahydrate, Disodium phosphate, di-Sodium hydrogen phosphate dodecahydrate

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Size/SKUAvailabilityPrice
1 kg
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€52.90
2.5 kg
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€125.00

About This Item

Linear Formula:
Na2HPO4 · 12H2O
CAS Number:
Molecular Weight:
358.14
PubChem Substance ID:
UNSPSC Code:
12161700
NACRES:
NA.25
EC Number:
231-448-7
MDL number:
Assay:
98.5-102.5% (T)
Form:
crystals

€52.90


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Quality Segment

agency

meets analytical specifications of BP, meets analytical specifications of Ph. Eur.

assay

98.5-102.5% (T)

form

crystals

quality

meets analytical specification of Ph. Eur., BP, E339

impurities

reducing matter, complies, residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤1.0% NaH2PO4, 57-61% water (Karl Fischer)

loss

57-61% loss on drying

pH

8.4-9.6 (20 °C, 1%)

anion traces

chloride (Cl-): ≤10 mg/kg, fluoride (F-): ≤10 mg/kg, sulfate (SO42-): ≤100 mg/kg

cation traces

As: ≤1 mg/kg, Cd: ≤1 mg/kg, Cu: ≤20 mg/kg, Fe: ≤10 mg/kg, Hg: ≤1 mg/kg, K: ≤50 mg/kg, Pb: ≤4 mg/kg, Zn: ≤10 mg/kg

suitability

complies for appearance of solution

SMILES string

O.O.O.O.O.O.O.O.O.O.O.O.[Na+].[Na+].OP([O-])([O-])=O

InChI

1S/2Na.H3O4P.12H2O/c;;1-5(2,3)4;;;;;;;;;;;;/h;;(H3,1,2,3,4);12*1H2/q2*+1;;;;;;;;;;;;;/p-2

InChI key

DGLRDKLJZLEJCY-UHFFFAOYSA-L

Application


  • Study of the Influence of Alkalizing Components on Matrix Pellets Prepared by Extrusion/Spheronization: This publication examines the effects of sodium phosphate dibasic dodecahydrate as an alkalizing agent in matrix pellets, showcasing its application in improving the physicochemical properties of pellets, which are crucial for controlled drug delivery systems (Hamedelniel EI, Bajdik J, Kasa P Jr, Pintye-Hodi K, 2012).


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This Item
71663716491.06573
description

meets analytical specification of Ph. Eur., BP, E339, 98.5-102.5% (T)

description

tested according to Ph. Eur.

description

BioXtra, ≥99.0% (T)

description

crystalline, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

form

crystals

form

crystalline

form

crystals

form

crystalline, solid

assay

98.5-102.5% (T)

assay

98.5-102.5%

assay

≥99.0% (T)

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

500

anion traces

chloride (Cl-): ≤10 mg/kg, sulfate (SO42-): ≤100 mg/kg, fluoride (F-): ≤10 mg/kg

anion traces

-

anion traces

chloride (Cl-): ≤5 mg/kg, fluoride (F-): ≤5 mg/kg, sulfate (SO42-): ≤50 mg/kg

anion traces

-

pH

8.4-9.6 (20 °C, 1%)

pH

-

pH

8.8-9.4 (25 °C, 0.1 M in H2O)

pH

9.0-9.3 (20 °C, 50 g/L in H2O)

impurities

reducing matter, complies, ≤0.001% heavy metals (as Pb), 57-61% water (Karl Fischer), residual solvents, complies, ≤1.0% NaH2PO4

impurities

-

impurities

insoluble matter, passes filter test

impurities

-


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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