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Merck

ED

Ethylenediaminetetraacetic acid

purified grade, ≥98.5%, powder

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

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About This Item

Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS Number:
Molecular Weight:
292.24
NACRES:
NA.28
PubChem Substance ID:
eCl@ss:
39030907
UNSPSC Code:
12352116
EC Number:
200-449-4
MDL number:
Beilstein/REAXYS Number:
1716295

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InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

grade

purified grade

assay

≥98.5%

form

powder

reaction suitability

reagent type: chelator

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

Quality Level

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1 of 4

This Item
E9884RDD0174005-OP
grade

purified grade

grade

ACS reagent

grade

ACS reagent

grade

-

assay

≥98.5%

assay

99.4-100.6%

assay

99.4-100.6%

assay

≥99.5%

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

100

mp

250 °C (dec.) (lit.)

mp

250 °C (dec.) (lit.)

mp

250 °C (dec.) (lit.)

mp

-

form

powder

form

powder

form

powder

form

crystalline powder (Fine)

pH

2.5 (23 °C, 10 g/L)

pH

2.5 (23 °C, 10 g/L)

pH

2.5 (23 °C, 10 g/L)

pH

2.5 (23 °C, 10 g/L)

General description

Ethylenediaminetetraacetic acid (EDTA) is an affordable chelating agent. It is an aminopolycarboxylic acid and a hexadentate ligand and forms octahedral complex with cations. Ethylenediaminetetraacetic acid (EDTA) is not recommended for phytoremediation as it can leach into natural water resources. It is used in cosmetics and pharmaceutical industry. It triggers platelet aggregation in pseudothrombocytopenia. In chelation therapy, it elicits protection from oxidative damage during blood and lipid peroxidation and may be useful to treat cardiovascular and carbon tetrachloride induced liver fibrosis.

Application

Ethylenediaminetetraacetic acid may be used:
  • as a component of staining buffer
  • as buffer component for incubating epithelial cell adhesion molecule (EpCAM+) cells with fluorescein isothiocyanate (FITC)-conjugated antibody for cell sorting studies
  • for treating epithelial cells for isolation of mucosal myofibroblasts

pictograms

Health hazardExclamation mark

signalword

Warning

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

target_organs

Respiratory Tract

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - STOT RE 2 Inhalation

wgk

WGK 3


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Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis
Bartholome B, et al.
Faseb Journal, 18(1), 70-80 (2004)
Functional modulation of Crohn?s disease myofibroblasts by anti-tumor necrosis factor antibodies
Di Sabatino A, et al.
Gastroenterology, 133(1), 137-149 (2007)
Induced Plant Accumulation of Lithium
Kavanagh L, et al.
Geostandards Newsletter, 8(2), 56-56 (2018)
The phenotypes of pluripotent human hepatic progenitors
Schmelzer E, et al.
Stem Cells, 24(8), 1852-1858 (2006)
Ethylenediaminetetraacetic acid induces antioxidant and anti-inflammatory activities in experimental liver fibrosis
Gonzalez-Cuevas J, et al.
Redox Report, 16(2), 62-70 (2011)

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