The solubility of this product has not been determined. However, the cell culture tested (±)-α-Lipoic acid, product T1395, is soluble at 50 mg/mL in ethanol. Similar solubility is expected for this item. In addition, various sources indicate this compound is also soluble in DMSO, acetonitrile, and chloroform. This information has not been validated.
07039
(R)-(+)-α-Lipoic acid
≥98.0% (HPLC)
Synonyme(s) :
(R)-(+)-1,2-Dithiolane-3-pentanoic acid, (R)-6,8-Dithiooctanoic acid, (R)-6,8-Thioctic acid
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A propos de cet article
Formule empirique (notation de Hill) :
C8H14O2S2
Numéro CAS:
Poids moléculaire :
206.33
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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assay
≥98.0% (HPLC)
optical purity
enantiomeric excess: ≥98.0% (HPLC)
mp
48-52 °C (lit.)
storage temp.
−20°C
SMILES string
OC(=O)CCCC[C@@H]1CCSS1
InChI
1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1
InChI key
AGBQKNBQESQNJD-SSDOTTSWSA-N
Biochem/physiol Actions
(R)-(+)-α-Lipoic acid was shown to significantly increase pyruvate oxidation while abrogating fatty acid oxidation in rat hepatocytes. These effects make R-(+)-α-Lipoic acid a promising treatment option for the treatment of Type II diabetes.[1] It is a biological antioxidant with prooxidant activities[2][3], its therapeutic potential is widely investigated[4][5][6], e.g. in the treatment for Alzheimer′s disease.[7]
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Analysis Note
identity confirmed by LC-MS
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Cet article | |||
|---|---|---|---|
| description ≥98.0% (HPLC) | description ≥97% (HPLC) | description analytical standard | description European Pharmacopoeia (EP) Reference Standard |
| Quality Level 100 | Quality Level 100, 200 | Quality Level 100 | Quality Level - |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| assay ≥98.0% (HPLC) | assay ≥97% (HPLC) | assay ≥98.0% (HPLC) | assay - |
| optical purity enantiomeric excess: ≥98.0% (HPLC) | optical purity enantiomeric excess: ≥98.0% (HPLC) | optical purity - | optical purity - |
| mp 48-52 °C (lit.) | mp - | mp 48-52 °C (lit.) | mp - |
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Classe de stockage
11 - Combustible Solids
wgk
WGK 3
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What is REF 07039 Lipoic Acid soluble in?
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