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G5419

Anti-GAD67 Antibody

Name: Anti-GAD67 Antibody
Brand: SIGMA
Price: 640 EUR

clone K-87, purified antibody

Synonyme(s) :

Anti-GAD 67

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À vous/Référence	Disponibilité	Prix
100 μg	Vérifier la disponibilité des articles du panier	640,00 €

A propos de cet article

MDL number:

MFCD06202147

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

K-87, monoclonal

Application:

IHC (p), WB

Citations:

640,00 €

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Propriétés

Nom du produit

Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse, clone K-87, purified antibody

biological source

mouse

Quality Segment

200

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

K-87, monoclonal

mol wt

antigen 67 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:500-1:20,000 (with antigen-retrieval step), western blot: 1:500-1:20,000 using mouse brain extract

isotype

IgG1κ

UniProt accession no.

Q99259

shipped in

dry ice

storage temp.

−70°C

target post-translational modification

unmodified

Gene Information

human ... GAD1(2571)
mouse ... Gad1(14415)
rat ... Gad1(24379)

Description

General description

Glutamic Acid Decarboxylase 67 (GAD67) is encoded by the gene glutamic acid decarboxylase 1 (GAD1). GAD1 gene is located on the human chromosome at 2q31.1. GAD67 is localized in the dendrites and cell bodies.

Immunogen

This peptide does not share homology with GAD65.

synthetic peptide from mouse GAD67 (amino acids 87-106).

Application

Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody is suitable for use in immunoblot, western blot (at 1:500-1:20,000 dilutions using mouse brain extract) and immunohistochemistry (at 1:500-1:20,000 dilutions in mouse brain sections).

Monoclonal anti-glutamic acid decarboxylase 67 (GAD67) antibody produced in mouse has been used in:

immunohistofluorescence[1]
western blotting
immunohistochemistry[2].

Biochem/physiol Actions

Glutamic Acid Decarboxylase 67 (GAD67) is involved in the production of γ-amino butyric acid (GABA), a inhibitory neurotransmitter in the central nervous system (CNS). Deficiency of GAD67 leads to psychosis, schizophrenia and bipolar diseases.

Reacts specifically with GAD67. Does not crossreact with GAD65.

Physical form

Solution in phosphate buffered saline containing 0.01% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Cet article	G1166	SAB4200232	G5038
Sigma-Aldrich G5419 Monoclonal Anti-Glutamic Acid Decarboxylase 67 (GAD67) antibody produced in mouse	Sigma-Aldrich G1166 Monoclonal Anti-Glutamic Acid Decarboxylase 65 antibody produced in mouse	Sigma-Aldrich SAB4200232 Anti-GAD65 antibody , Mouse monoclonal	$Anti-Glutamic Acid Decarboxylase 65 (5-22) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich G5038 Anti-Glutamic Acid Decarboxylase 65 (5-22) antibody produced in rabbit
biological source mouse	biological source mouse	biological source mouse	biological source rabbit
species reactivity rat, mouse, human	species reactivity mammals (and some lower vertebrates)	species reactivity human, mouse, monkey, rat	species reactivity human, mouse, rat, pig, monkey
Gene Information human ... GAD1(2571) mouse ... Gad1(14415) rat ... Gad1(24379)	Gene Information human ... GAD2(2572) mouse ... Gad2(14417)	Gene Information human ... GAD2(2572) mouse ... Gad2(14417) rat ... Gad2(24380)	Gene Information human ... GAD2(2572) mouse ... Gad2(14417) rat ... Gad2(24380)
clone K-87, monoclonal	clone GAD-6, monoclonal	clone N-GAD65, monoclonal	clone polyclonal
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form purified antibody	antibody form purified immunoglobulin	antibody form purified from hybridoma cell culture	antibody form IgG fraction of antiserum

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Classe de stockage

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c