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M7939

Anti-Myosin IIB, non-muscle antibody produced in rabbit

Name: Anti-Myosin IIB, non-muscle antibody produced in rabbit
Brand: SIGMA
Price: 518 EUR
Availability: InStock

affinity isolated antibody, buffered aqueous solution

Synonym(e):

Anti-Myosin-10

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Ihnen/SKU	Verfügbarkeit	Preis
0.2 mL	Ab HEUTE lieferbarvonSchnelldorf	518,00 €

Über diesen Artikel

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03455611

Conjugate:

unconjugated

Clone:

polyclonal

Application:

WB CL

Citations:

518,00 €

Ab HEUTE lieferbarDetails

Für Ihr Target ist ein rekombinanter, konservierungsmittelfreier Antikörper verfügbar. Probieren Sie ZRB2186

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Eigenschaften

biological source

rabbit

Quality Segment

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~200 kDa

species reactivity

rat, human, canine

technique(s)

western blot (chemiluminescent): 1:200 using whole cell extracts of cultured dog MDCK kidney cells, cultured rat NRK cells, and cultured human Jurkat cells.

UniProt accession no.

P35580

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

rat ... Myh10(79433)

Beschreibung

General description

Myosin IIB (nonmuscle) is a relatively abundant, widespread two headed myosin composed of an N-terminal motor domain, a light chain binding neck region, a coiled-coil region, and a nonhelical C-terminal domain. It forms a heterohexamer composed of a pair of heavy chains and two pairs of light chains. Myosin IIB is expressed in embryonic cardiac myocytes.

Immunogen

Synthetic peptide corresponding to amino acid residues 1965-1976 of the heavy chain of human myosin IIB (nonmuscle) conjugated to KLH. This sequence is identical in rabbit and differs by one and two amino acids from the respective bovine and rat sequences.

Application

Anti-Myosin IIB, non-muscle antibody produced in rabbit has been used in:

immunoblotting
stimulated emission depletion (STED) nanoscopy
immunofluorescence

Biochem/physiol Actions

Anti-Myosin IIB, non-muscle antibody is specific for the heavy chain of human myosin IIB (nonmuscle). The antibody also reacts with myosin in dogs and rats.

Myosin IIB plays a key role in the COS-7 cell cytokinesis and is need for the initiation of ring constriction.

Myosins are actin-dependent motors that have 15 classes based on their phylogenetics . Myosin IIb regulates memory and synaptic plasticity functions. Nonmuscle myosin IIb has been implicated in fibroblast movement and erythroblast enucleation .

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel	M8064	M7648	M7523
Sigma-Aldrich M7939 Anti-Myosin IIB, non-muscle antibody produced in rabbit	Sigma-Aldrich M8064 Anti-Myosin IIA, non muscle antibody produced in rabbit	Sigma-Aldrich M7648 Anti-Myosin (Skeletal and Smooth) antibody produced in rabbit	Sigma-Aldrich M7523 Anti-Myosin (Skeletal) antibody produced in rabbit
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form whole antiserum	antibody form whole antiserum
mol wt antigen ~200 kDa	mol wt antigen ~200 kDa	mol wt -	mol wt -
shipped in dry ice	shipped in dry ice	shipped in dry ice	shipped in dry ice

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Lagerklasse

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c