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SML3303

EU1622-1

≥98%

Synonym(s):

5-​(4-​chlorophenyl)​-​6-​methyl-​3-​[2-​oxo-​2-​(1-​pyrrolidinyl)​ethyl]​-thieno[2,​3-​d]​pyrimidin-​4(3H)​-​one

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About This Item

Empirical Formula (Hill Notation):
C19H18ClN3O2S
CAS Number:
691386-78-4
Molecular Weight:
387.88
UNSPSC Code:
51111800
MDL number:
MFCD05238155
Assay:
≥98%
Form:
powder
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Quality Segment

100

assay

≥98%

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

CC1=C(C2=C(N=CN(C2=O)CC(N3CCCC3)=O)S1)C4=CC=C(C=C4)Cl

InChI

1S/C19H18ClN3O2S/c1-12-16(13-4-6-14(20)7-5-13)17-18(26-12)21-11-23(19(17)25)10-15(24)22-8-2-3-9-22/h4-7,11H,2-3,8-10H2,1H3

InChI key

KHRRGSKOOLJVDL-UHFFFAOYSA-N

Biochem/physiol Actions

EU1622-1 is pan-NMDAR (N-methyl d-aspartate receptors) positive allosteric modulator that decrease the conductance in all GluN2 NMDARs. EU1622-1 reduces calcium permeability. It has minimal effects on AMPA receptors.
pan-NMDAR (N-methyl d-aspartate receptors) PAM that decrease conductance and reduce calcium permeability

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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