SML3333
Dianhydrogalactitol
≥95% (HPLC)
Synonym(s):
1,2:5,6-Dianhydrogalactitol, 1,2:5,6-Diepoxydulcitol, DAG, NSC-132313, VAL-083
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 5 mg | Please contact Customer Service for Availability | $128.00 | |
| 25 mg | Please contact Customer Service for Availability | $518.00 |
About This Item
Empirical Formula (Hill Notation):
C6H10O4
CAS Number:
Molecular Weight:
146.14
UNSPSC Code:
12352200
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
$128.00
Please contact Customer Service for Availability
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
O[C@H]([C@@]1(CO1)[H])[C@H]([C@]2(CO2)[H])O
InChI
1S/C6H10O4/c7-5(3-1-9-3)6(8)4-2-10-4/h3-8H,1-2H2/t3-,4+,5+,6-
InChI key
AAFJXZWCNVJTMK-GUCUJZIJSA-N
Biochem/physiol Actions
Blood brain barrier penetrant alkylating agent that causes N7-guanine alkylation
Dianhydrogalactitol is a blood brain barrier penetrant and potent alkylating agent that causes N7-guanine alkylation and inter-strand DNA crosslinks that induces cell cycle arrest followed by apoptosis. Dianhydrogalactitol exhibits potent antitumor activity in number of clinical models including metastatic NSCLC resistant to TKI and glioblastoma multiforme.
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This Item | |||
|---|---|---|---|
| assay ≥95% (HPLC) | assay - | assay - | assay 99% |
| form powder | form solid | form powder | form liquid |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| storage temp. −20°C | storage temp. - | storage temp. 2-30°C | storage temp. - |
| solubility DMSO: 2 mg/mL, clear | solubility - | solubility - | solubility - |
| color white to beige | color - | color - | color - |
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML3333-25MG | 04065268085462 |
| SML3333-5MG | 04065268085479 |