SML3612
Ganoderic acid D
≥95% (HPLC)
Synonym(s):
(7β)-7-Hydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid, GAD
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About This Item
Empirical Formula (Hill Notation):
C30H42O7
CAS Number:
Molecular Weight:
514.65
UNSPSC Code:
12352106
NACRES:
NA.21
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Quality Segment
assay
≥95% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
O[C@H]1C[C@@H]2[C@](CCC(=O)C2(C)C)(C3=C1[C@]4([C@@]([C@H](CC4=O)[C@@H](CC(=O)CC(C)C(=O)O)C)(CC3=O)C)C)C
InChI key
YTVGSCZIHGRVAV-IYAQLQCNSA-N
Biochem/physiol Actions
Ganoderic acid D is one of major triterpenes isolated from Ganoderma lucidum that exhibit potent anticancer properties. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate, and pyruvate and acetyl-coenzyme production through SIRT3 upregulation via acetylated cyclophilin D inhibition.
Major triterpenes isolated from Ganoderma lucidum that exhibit potent anticancer properties
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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