SML3745
SJG-136
≥95% (HPLC)
Synonym(s):
(11aS,11′aS)-8,8′-[1,3-Propanediylbis(oxy)]bis[1,2,3,11a-tetrahydro-7-methoxy-2-methylene-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one], NSC 694501, PBD dimer SJG-136, SG2000
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About This Item
Empirical Formula (Hill Notation):
C31H32N4O6
CAS Number:
Molecular Weight:
556.61
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
Quality Segment
assay
≥95% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
Highly potent DNA cross-linking agent that binds in the minor groove of DNA.
SJG-136 is a highly potent DNA cross-linking agent that binds in the minor groove of DNA. SJG-136 exhibits potent anticancer activity in numerous cancer cell lines and in vivo. It exhibits significant inhibitory effect against Src activity.
SJG-136 is a highly potent DNA cross-linking agent that binds in the minor groove of DNA. SJG-136 exhibits potent anticancer activity in numerous cancer cell lines and in vivo. It exhibits significant inhibitory effect against Src activity.
Disclaimer
Hygroscopic
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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