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SML3926

YM-53601 hydrochloride

≥98% (HPLC)

Synonym(s):

(E)-2-[2-fluoro-2-(quinuclidin-3-ylidene) ethxy]-9H-carbazole monohydrochloride, 2-[(2E)-2-(1-Azabicyclo[2.2.2]oct-3-ylidene)-2-fluoroethoxy]-9H-carbazole hydrochloride, YM 53601

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About This Item

Empirical Formula (Hill Notation):
C21H21FN2O·HCl
CAS Number:
Molecular Weight:
372.86
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

-10 to -25°C

Biochem/physiol Actions

Squalene synthase inhibitor.


YM-53601 is a cell penetrant and potent squalene synthase inhibitor inhibits cholesterol biosynthesis in rodents. YM-53601 lowers cholesterol levels and triglyceride levels better than HMG-CoA reductase inhibitor (prevastatin) and fibrate (fenofibrate.).

Disclaimer

Hygroscopic


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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