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About This Item
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(C1=CC=CO1)NC(NC2=CC=C3C(C=CC=C3)=C2)C(Cl)(Cl)Cl
Biochem/physiol Actions
Potent blocker of all Orai channels indiscriminately with an IC50 value of 195 nM in blocking SOCE in primary T cells.
Pan-Orai inhibitor 5D is a potent blocker of all Orai channels indiscriminately with an IC50 value of 195 nM in blocking SOCE in primary T cells. pan-Orai inhibitor 5D potently inhibits effector T-cell function and IL-2 production.
Pan-Orai inhibitor 5D is a potent blocker of all Orai channels indiscriminately with an IC50 value of 195 nM in blocking SOCE in primary T cells. pan-Orai inhibitor 5D potently inhibits effector T-cell function and IL-2 production.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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