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SML4120

BIBP3226 trifluoroacetate

≥95% (HPLC)

Synonym(s):

BIBP 3226 TFA salt, BIBP-3226 TFA salt, Diphenylacetyl-D-Arg-4-hydroxybenzylamide, trifluoroacetate salt, N2-(Diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-D-arginine amide, trifluoroacetate salt, (R)-N2-(Diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-argininamide, trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C27H31N5O3 · xC2HF3O2
CAS Number:
1068148-47-9
Molecular Weight:
473.57 (free base basis)
MDL number:
MFCD00938562
NACRES:
NA.28
Assay:
≥95% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

assay

≥95% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC(C=C1)=CC=C1CNC([C@@H](CCCNC(N)=N)NC(C(C2=CC=CC=C2)C3=CC=CC=C3)=O)=O

Biochem/physiol Actions

Potent and selective non-peptide neuropeptide Y receptor Y1 antagonist in vitro and in vivo.
BIBP3226 is a potent and selective non-peptide neuropeptide Y receptor Y1 antagonist (Ki = 7 nM against neuropeptide Y binding to receptor Y1) in vitro and in vivo. BIBP3226 selectively blocks Y1 receptor-mediated rabbit saphenous vein contraction (pA2 = 7.36), but not receptor Y2- or Y3-dependent biological effects.

Disclaimer

Hygroscopic

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H315

Hazard Classifications

Skin Irrit. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

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