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About This Item
Empirical Formula (Hill Notation):
C20H23N7O2
CAS Number:
Molecular Weight:
393.44
NACRES:
NA.21
Pricing and availability is not currently available.
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
NC(NC(C1=NC(C2=CC(C=CC=C3)=C3O2)=C(N4CCCCCC4)N=C1N)=O)=N
Biochem/physiol Actions
Cell penetrant, selective and potent multi-targeting bioenergetic inhibitor of succinate dehydrogenase and the F1Fo-ATP synthase in Mycobacterium tuberculosis; bactericidal antibiotic in MTB.
BB2-50F, an amiloride derivative, is a cell penetrant, selective and potent multi-targeting bioenergetic inhibitor of succinate dehydrogenase and the F1Fo-ATP synthase in Mycobacterium tuberculosis. BB2-50F act as fast acting bactericidal antibiotic in both replicating and nonreplicating cultures of M. tuberculosis (MIC = 2.6 µM in M. tuberculosis mc2 6230). BB2-50F is a potent inhibitor of bacterial motility.
BB2-50F, an amiloride derivative, is a cell penetrant, selective and potent multi-targeting bioenergetic inhibitor of succinate dehydrogenase and the F1Fo-ATP synthase in Mycobacterium tuberculosis. BB2-50F act as fast acting bactericidal antibiotic in both replicating and nonreplicating cultures of M. tuberculosis (MIC = 2.6 µM in M. tuberculosis mc2 6230). BB2-50F is a potent inhibitor of bacterial motility.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| SML4136-25MG | 04065272636520 |
| SML4136-5MG | 04065272636537 |