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SML4169

Romifidine hydrochloride

≥98% (HPLC), powder, α2-adrenergic receptor

Synonym(s):

2-(2-Bromo-6-fluoroanilino)-2-imidazoline hydrochloride, N-(2-Bromo-6-fluorophenyl)-4,5-dihydro-1H-imidazol-2-amine hydrochloride, STH 2130-Cl

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About This Item

Empirical Formula (Hill Notation):
C9H9BrFN3.HCl
CAS Number:
65896-14-2
Molecular Weight:
294.55
MDL number:
MFCD16293882
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
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Quality Segment

100

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

H2O: 2 mg/mL, clear

storage temp.

-10 to -25°C

SMILES string

FC1=CC=CC(Br)=C1NC2=NCCN2.Cl

Application

Romifidine hydrochloride may be used to study its effects on sedation and pain management in animal models.

Biochem/physiol Actions

Romifidine is an α2-adrenergic receptor (α2-adrenoceptor) agonist with in vivo sedative and analgesic efficacy. Romifidine depresses excitatory postsynaptic potential in a neonatal rat hemisected spinal cord preparation ex vivo (high/low intensity e.p.s.p. EC50 = 23.4/22.0 µM), reversible by the selective α2-adrenoceptor antagonist atipamezole.

Disclaimer

Hygroscopic

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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