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About This Item
Empirical Formula (Hill Notation):
C12H16O4
CAS Number:
Molecular Weight:
224.25
MDL number:
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
CC(CCC(C1=C(C=C(OC1=O)C)O)=O)C
Application
Pogostone may be used:
- to study its insecticidal activity against Spodoptera litura (Fabricius) and Spodoptera exigua (Hübner)
- to study its effects on adipose tissue inflammation in vitro and in vivo
- to study its effects on osteolytic bone metastases in mice and investigate the molecular mechanisms of pogostone against cancer-induced osteoclast formation and cancer cell proliferation or migration in vitro
Biochem/physiol Actions
Pogostone is an active ingredient isolated from the essential oil of Pogostemon cablin (patchouli oil) that exhibits various pharmacological properties, including anti-inflammatory and anti-cancer activities. Pogostone attenuates high-fat diet–induced nonalcoholic fatty liver disease (NAFLD) in mice through inhibition of NLRP3 inflammasome signaling.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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