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SML4318

MALP-2 trifluoroacetate

≥95% (HPLC)

Synonym(s):

(2R)-MALP 2 trifluoroacetate, (2R)-MALP-2 trifluoroacetate, (2R)-MALP2 trifluoroacetate, MALP 2 trifluoroacetate, MALP2 trifluoroacetate, R-MALP 2 trifluoroacetate, R-MALP-2 trifluoroacetate, R-MALP2 trifluoroacetate, Synthetic (2R)-Macrophage-Activating LipoPeptide-2 trifluoroacetate, MALP 2 trifluoroacetate, MALP2 trifluoroacetate, P2C‐GNNDESNISFKEK trifluoroacetate, S-[2,3-bis(Palmityloxy)-(2R)-propyl-cysteinyl-GNNDESNISFKEK trifluoroacetate

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About This Item

Empirical Formula (Hill Notation):
C99H167N19O30S · xC2HF3O2
Molecular Weight:
2135.56 (free base basis)
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
(Powder or Lyophilized powder or film)
Storage condition:
desiccated
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Quality Segment

100

assay

≥95% (HPLC)

form

(Powder or Lyophilized powder or film)

storage condition

desiccated

color

white to off-white

storage temp.

-10 to -25°C

Biochem/physiol Actions

MALP-2 is a synthetic diacylated lipopeptide that exerts its in vitro and in vivo immunostimulatory properties via toll-like receptor 2 & 6 heterodimeric complex (TLR2/6) with the (2R)-MALP-2 being >100 times more potent than the (2S)-isomer in stimulating the release of cytokines, chemokines, and NO (C3H/HeJ murine macrophages & primay human monocytes). Unlike the Mycoplasma fermentas-derived MALP-2, the synthetic peptide contains dipalmityloxyl (no stearoyloxyl) and has (2R) instead of racemic (2R/S) configuration. Typical dosing range in culture: 5-200 ng/mL (2.34-936 nM)

Disclaimer

Hygroscopic, store with desiccant

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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