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About This Item
Empirical Formula (Hill Notation):
C14H18N4O9S
Molecular Weight:
418.38
UNSPSC Code:
12352200
Assay:
≥95% (NMR)
Form:
powder
Quality Segment
assay
≥95% (NMR)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
shipped in
wet ice
storage temp.
-10 to -25°C
Biochem/physiol Actions
DSSO-carbamate is an advanced crosslinker optimized for cross-linking mass spectrometry (XL-MS) applications, offering superior chemical stability and reactivity compared to DSSO. By replacing ester groups with carbamates, it resists retro-Michael degradation, ensuring higher recovery rates for crosslinks and monolinks under physiological conditions. This enhanced performance facilitates precise structural mapping of flexible and multiconformational proteins, significantly improving integration with computational tools like AlphaFold2. DSSO-carbamate’s improved sensitivity, stability, and structural accuracy make it a valuable addition for proteomics, particularly in resolving dynamic protein conformations and interactions.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
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